Evaluation of chitosan microparticles containing curcumin and crosslinked with sodium tripolyphosphate produced by spray drying

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorParize, Alexandre Luis-
Autor(es): dc.creatorStulzer, Hellen Karine-
Autor(es): dc.creatorLaranjeira, Mauro César Marghetti-
Autor(es): dc.creatorBrighente, Inês Maria da Costa-
Autor(es): dc.creatorSouza, Tereza Cristina Rozone de-
Data de aceite: dc.date.accessioned2025-03-18T19:24:35Z-
Data de disponibilização: dc.date.available2025-03-18T19:24:35Z-
Data de envio: dc.date.issued2017-12-07-
Data de envio: dc.date.issued2017-12-07-
Data de envio: dc.date.issued2012-
Fonte completa do material: dc.identifierhttp://repositorio.unb.br/handle/10482/28331-
Fonte completa do material: dc.identifierhttps://dx.doi.org/10.1590/S0100-40422012000600011-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/967334-
Descrição: dc.descriptionThe aim of this study was to encapsulate curcumin into chitosan, using sodium tripolyphosphate (TPP) as an ionic crosslinker by the spray drying method. The influence of TPP on the properties of the final product, such as solubility, morphology, loading efficiency, thermal behavior, swelling degree and release profiles, was evaluated. The microparticles had a spherical morphology (0.5-20 µm) with no apparent porosity or cracks. Results indicated the formation of a polymeric network, which ensures effective protection for curcumin. Controlled-release studies were carried out at pH 1.2 and 6.8, to observe the influence of pH on curcumin release while the mechanism was analyzed using the Korsmeyer-Peppas equation.-
Descrição: dc.descriptionInstituto de Química (IQ)-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherSociedade Brasileira de Química-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rightsQuímica Nova - (CC BY-NC) - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600011&lng=en&nrm=iso&tlng=en. Acesso em: 22 out. 2020.-
Palavras-chave: dc.subjectQuitosana-
Palavras-chave: dc.subjectCurcumina-
Palavras-chave: dc.subjectSecagem-
Título: dc.titleEvaluation of chitosan microparticles containing curcumin and crosslinked with sodium tripolyphosphate produced by spray drying-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional – UNB - Rep. 1

Não existem arquivos associados a este item.