The antioxidant action of Polypodium leucotomos extract and kojic acid : reactions with reactive oxygen species

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorGomes, Anderson de Jesus-
Autor(es): dc.creatorLunardi, Claure Nain-
Autor(es): dc.creatorGonzalez, Salvador-
Autor(es): dc.creatorTedesco, Antonio Claudio-
Data de aceite: dc.date.accessioned2024-10-23T16:16:19Z-
Data de disponibilização: dc.date.available2024-10-23T16:16:19Z-
Data de envio: dc.date.issued2012-12-14-
Data de envio: dc.date.issued2012-12-14-
Data de envio: dc.date.issued2001-11-
Fonte completa do material: dc.identifierhttp://repositorio.unb.br/handle/10482/11814-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S0100-879X2001001100018-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/904137-
Descrição: dc.descriptionTwo natural products Polypodium leucotomos extract (PL) and kojic acid (KA) were tested for their ability to scavenge reactive oxygen species (•OH, •O2-, H2O2, 1O2) in phosphate buffer. Hydroxyl radicals were generated by the Fenton reaction, and the rate constants of scavenging were 1.6 x 109 M-1 s-1 for KA and 1.0 x 109 M-1 s-1 for PL, similar to that of ethanol (1.4 x 109 M-1 s-1). With superoxide anions generated by the xanthine/hypoxanthine system, KA and PL (0.2-1.0 mg/ml) inhibited •O2-dependent reduction of nitroblue tetrazolium by up to 30 and 31%, respectively. In the detection of 1O2 by rose bengal irradiation, PL at 1.0 mg/ml quenched singlet oxygen by 43% relative to azide and KA by 36%. The present study demonstrates that PL showed an antioxidant effect, scavenging three of four reactive oxygen species tested here. Unlike KA, PL did not significantly scavenge hydrogen peroxide.-
Formato: dc.formatapplication/pdf-
Publicador: dc.publisherAssociação Brasileira de Divulgação Científica-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rightsBrazilian Journal of Medical and Biological Research - Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)). Fonte: http://www.scielo.br/scielo.php?script=sci_serial&pid=0100-879X&lng=pt&nrm=iso. Acesso em: 8 nov. 2012.-
Palavras-chave: dc.subjectPolipódio-
Palavras-chave: dc.subjectAntioxidantes-
Palavras-chave: dc.subjectRadicais livres (Química)-
Palavras-chave: dc.subjectÁcido kójico-
Título: dc.titleThe antioxidant action of Polypodium leucotomos extract and kojic acid : reactions with reactive oxygen species-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional – UNB

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