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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | State Health Department of the Federal District | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | University Center of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | Central Laboratory of Public Health of the Federal District | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.contributor | University Hospital of Brasília, Department of Rheumatology | - |
Autor(es): dc.contributor | University of Brasília, Faculty of Medicine | - |
Autor(es): dc.creator | Fernandes, Geraldo Magela | - |
Autor(es): dc.creator | Motta, Felipe | - |
Autor(es): dc.creator | Sasaki, Lizandra Moura Paravidine | - |
Autor(es): dc.creator | Silva, Ângelo Pereira da | - |
Autor(es): dc.creator | Miranda, Andreza Monforte | - |
Autor(es): dc.creator | Carvalho, Aleida Oliveira de | - |
Autor(es): dc.creator | Gomides, Ana Paulo Monteiro | - |
Autor(es): dc.creator | Soares, Alexandre Anderson de Sousa Munhoz | - |
Autor(es): dc.creator | Santos Junior, Agenor de Castro Moreira dos | - |
Autor(es): dc.creator | Alves, Caroline de Oliveira | - |
Autor(es): dc.creator | Gomes, Ciro Martins | - |
Autor(es): dc.creator | Siracusa, Clara Correia de | - |
Autor(es): dc.creator | Araújo Júnior, David Alves de | - |
Autor(es): dc.creator | Silva, Dayde Lane Mendonça da | - |
Autor(es): dc.creator | Jesus, José Alfredo Lacerda de | - |
Autor(es): dc.creator | Costa, Karina Nascimento | - |
Autor(es): dc.creator | Castro, Maria Eduarda Canellas de | - |
Autor(es): dc.creator | Kurizky, Patricia Shu | - |
Autor(es): dc.creator | França, Paulo Sérgio | - |
Autor(es): dc.creator | Tristão, Rosana Maria | - |
Autor(es): dc.creator | Pereira, Yacara Ribeiro | - |
Autor(es): dc.creator | Castro, Luiz Claudio Gonçalves de | - |
Autor(es): dc.creator | Zaconeta, Alberto Carlos Moreno | - |
Autor(es): dc.creator | Albuquerque, Cleandro Pires de | - |
Autor(es): dc.creator | Mota, Licia Maria Henrique da | - |
Data de aceite: dc.date.accessioned | 2024-10-23T16:03:28Z | - |
Data de disponibilização: dc.date.available | 2024-10-23T16:03:28Z | - |
Data de envio: dc.date.issued | 2023-10-10 | - |
Data de envio: dc.date.issued | 2023-10-10 | - |
Data de envio: dc.date.issued | 2021-04-20 | - |
Fonte completa do material: dc.identifier | http://repositorio2.unb.br/jspui/handle/10482/46658 | - |
Fonte completa do material: dc.identifier | https://doi.org/10.2196%2F26477 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-4347-8886 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-6733-8722 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-6699-291X | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-2583-9921 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-0298-6929 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-8382-4333 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-2884-2210 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-4716-9543 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-8485-2603 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-9222-5666 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-3069-6884 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-9149-957X | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-7251-0331 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-5653-7411 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-3203-4806 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-3095-971X | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-8727-8328 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-5759-2727 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-8492-1605 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-1751-8506 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-5371-5486 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-9166-1837 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-6440-4395 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-9245-7504 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-8182-5121 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/capes/898732 | - |
Descrição: dc.description | Background: A growing body of evidence suggests that SARS-COV-2 infection during pregnancy may affect maternal-fetal outcomes and possibly result in implications for the long-term development of SARSCoV-2–exposed children. Objective: The PROUDEST (Pregnancy Outcomes and Child Development Effects of SARS-CoV-2 Infection Study) is a multicenter, prospective cohort study designed to elucidate the repercussions of COVID19 for the global health of mothers and their children. Methods: The PROUDEST trial comprises 2 prospective, sequential substudies. The PREGNANT substudy will clinically assess the effects of SARS-CoV-2 infection on pregnancy, childbirth, and puerperium from a mechanistic standpoint to elucidate the pregnancy-related inflammatory and immunological phenomena underlying COVID-19. Pregnant women aged 18-40 years who have been exposed (proven with laboratory tests) to SARS-CoV-2 (group A; n=300) will be compared to control subjects with no laboratory evidence of in-pregnancy exposure to the virus (group B; n=300). Subjects exposed to other infections during pregnancy will be excluded. The BORN substudy is a long-term follow-up study that will assess the offspring of women who enrolled in the prior substudy. It will describe the effects of SARS-CoV-2 exposure during pregnancy on children’s growth, neurodevelopment, and metabolism from birth up to 5 years of age. It includes two comparison groups; group A (exposed; n=300) comprises children born from SARS-CoV-2– exposed pregnancies, and group B (controls; n=300) comprises children born from nonexposed mothers. Results: Recruitment began in July 2020, and as of January 2021, 260 pregnant women who were infected with SARS-CoV-2 during pregnancy and 160 newborns have been included in the study. Data analysis is scheduled to start after all data are collected. Conclusions: Upon completion of the study, we expect to have comprehensive data that will provide a better understanding of the effects of SARS-CoV-2 infection and related inflammatory and immunological processes on pregnancy, puerperium, and infancy. Our findings will inform clinical decisions regarding the care of SARS-CoV-2–exposed mothers and children and support the development of evidence-based public health policies. | - |
Descrição: dc.description | Faculdade de Medicina (FMD) | - |
Descrição: dc.description | Faculdade UnB Ceilândia (FCE) | - |
Formato: dc.format | application/pdf | - |
Idioma: dc.language | en | - |
Direitos: dc.rights | Acesso Aberto | - |
Direitos: dc.rights | This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on http://www.researchprotocols.org, as well as this copyright and license information must be included. | - |
Palavras-chave: dc.subject | SARS-CoV-2 | - |
Palavras-chave: dc.subject | Desenvolvimento infantil | - |
Palavras-chave: dc.subject | Desenvolvimento embrionário | - |
Palavras-chave: dc.subject | Gravidez | - |
Título: dc.title | Pregnancy outcomes and child development effects of SARS-CoV-2 Infection (PROUDEST Trial) : protocol for a multicenter, prospective cohort study | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional – UNB |
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