Production of Brazilian human norovirus VLPs and comparison of purification methods

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorLamounier, Thaís Alves da Costa-
Autor(es): dc.creatorOliveira, Layssa Miranda de-
Autor(es): dc.creatorCamargo, Brenda Rabello de-
Autor(es): dc.creatorRodrigues, Kelly Barreto-
Autor(es): dc.creatorNoronha, Eliane Ferreira-
Autor(es): dc.creatorRibeiro, Bergmann Morais-
Autor(es): dc.creatorNagata, Tatsuya-
Data de aceite: dc.date.accessioned2024-10-23T15:58:37Z-
Data de disponibilização: dc.date.available2024-10-23T15:58:37Z-
Data de envio: dc.date.issued2017-12-07-
Data de envio: dc.date.issued2017-12-07-
Data de envio: dc.date.issued2015-10-
Fonte completa do material: dc.identifierhttp://repositorio.unb.br/handle/10482/29849-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S1517-838246420140925-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/896873-
Descrição: dc.descriptionNoroviruses (NVs) are responsible for most cases of human nonbacterial gastroenteritis worldwide. Some parameters for the purification of NV virus-like particles (VLPs) such as ease of production and yield were studied for future development of vaccines and diagnostic tools. In this study, VLPs were produced by the expression of the VP1 and VP2 gene cassette of the Brazilian NV isolate, and two purification methods were compared: cesium chloride (CsCl) gradient centrifugation and ion-exchange chromatography (IEC). IEC produced more and purer VLPs of NV compared to CsCl gradient centrifugation.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherSociedade Brasileira de Microbiologia-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rightsBrazilian Journal of Microbiology - All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License CC-BY (CC BY NC 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401265&lng=en&nrm=iso. Acesso em: 2 abr. 2018.-
Palavras-chave: dc.subjectVírus-
Palavras-chave: dc.subjectCromatografia de troca iônica-
Título: dc.titleProduction of Brazilian human norovirus VLPs and comparison of purification methods-
Tipo de arquivo: dc.typelivro digital-
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