Stress conditions in the host induce persister cells and influence biofilm formation by Staphylococcus epidermidis RP62A

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorFraiha, Rafael Ovando-
Autor(es): dc.creatorPereira, Ana Paula Ramos-
Autor(es): dc.creatorBrito, Eliana da Costa Alvarenga-
Autor(es): dc.creatorBorges, Clayton Luiz-
Autor(es): dc.creatorParente, Ana Flávia Alves-
Autor(es): dc.creatorPerdomo, Renata Trentin-
Autor(es): dc.creatorMacedo, Maria Ligia Rodrigues-
Autor(es): dc.creatorWeber, Simone Schneider-
Data de aceite: dc.date.accessioned2024-10-23T15:33:55Z-
Data de disponibilização: dc.date.available2024-10-23T15:33:55Z-
Data de envio: dc.date.issued2020-01-23-
Data de envio: dc.date.issued2020-01-23-
Data de envio: dc.date.issued2019-
Fonte completa do material: dc.identifierhttps://repositorio.unb.br/handle/10482/36247-
Fonte completa do material: dc.identifierhttps://doi.org/10.1590/0037-8682-0001-2018-
Fonte completa do material: dc.identifierhttp://orcid.org/0000-0002-4181-142X-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/886256-
Descrição: dc.descriptionINTRODUCTION: Studies have demonstrated that pathogens react to the harsh conditions in human tissues by inducing mechanisms that promote survival. METHODS: Persistence and biofilm-forming ability were evaluated during stress conditions that mimic those in the host. RESULTS: Carbon-source availability had a positive effect on Staphylococcus epidermidis RP62A adhesion during hypoxia, accompanied by a decrease in pH. In contrast, iron limitation led to decreased surface-adherent biomass, accompanied by an increase medium acidification and lactate levels. Interestingly, iron starvation and hypoxia induced persister cells in planktonic culture. CONCLUSIONS: These findings highlight the role of host stress in the virulence of S. epidermidis.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherSociedade Brasileira de Medicina Tropical - SBMT-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rightsOPEN ACCESS - https://creativecommons.org/licenses/by/4.0/ (CC BY)-
Palavras-chave: dc.subjectPersistência-
Palavras-chave: dc.subjectInanição-
Palavras-chave: dc.subjectVirulência (Microbiologia)-
Título: dc.titleStress conditions in the host induce persister cells and influence biofilm formation by Staphylococcus epidermidis RP62A-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional – UNB

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