Enterolobin induces rat paw oedema independently of PAF-Acether

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorFaria Neto, Hugo Caire de Castro-
Autor(es): dc.creatorCordeiro, Renato Sergio Balao-
Autor(es): dc.creatorMartins, Marco Aurélio-
Autor(es): dc.creatorSilva, A. C. V. Correira da-
Autor(es): dc.creatorBozza, Patricia Torres-
Autor(es): dc.creatorSousa, Marcelo Valle de-
Autor(es): dc.creatorMorhy, Lauro-
Data de aceite: dc.date.accessioned2024-10-23T15:31:07Z-
Data de disponibilização: dc.date.available2024-10-23T15:31:07Z-
Data de envio: dc.date.issued2011-11-16-
Data de envio: dc.date.issued2011-11-16-
Data de envio: dc.date.issued1991-
Fonte completa do material: dc.identifierhttp://repositorio.unb.br/handle/10482/9587-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/885107-
Descrição: dc.descriptionThe potential participation of PAF-acether (PAF) on the paw oedema triggered by enterolobin was investigated. Intraplantar injections of enterolobin (5-20 µg/paw) yielded a dose response curve for oedema which appeared after 30 min, peaked in the interval between 2-4 h and faded after 24 h. The pre-treatment with BN 52021, but not with other PAF antagonists such as PCA 4248 or WEB 2086, significantly blocked enterolobin-induced oedema. To clarify better the discrepant results obtained with the PAF antagonists, desensitization to PAF was perfomed. The oedema triggered by enterolobin was not modified in PAF desensitized animals. It was concluded that the paw inflammation induced by enterolobin does not require PAF mechanism.-
Formato: dc.formatapplication/pdf-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rights"Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0). Fonte: http://www.scielo.br/scielo.php?script=sci_serial&pid=0074-0276&nrm=iso&rep=&lng=pt. Acesso em: 16 nov. 2011.-
Palavras-chave: dc.subjectProteínas-
Palavras-chave: dc.subjectEdema-
Título: dc.titleEnterolobin induces rat paw oedema independently of PAF-Acether-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional – UNB

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