Persistent, new‑onset symptoms and mental health complaints in Long COVID in a Brazilian cohort of non‑hospitalized patients

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Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorArmed Forces Hospital, Learning and Research Technical Board,-
Autor(es): dc.contributorCentral Laboratory of Public Health of the Federal District, Brasília, Brazil-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorFederal District Strategic Health Management Institute, Brasília, Brazil-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorCentral Institute of Sciences, Technology for Gene Therapy Laboratory-FAV, University of Brasília-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.contributorCentral Institute of Sciences, Technology for Gene Therapy Laboratory-FAV, University of Brasília-
Autor(es): dc.contributorDepartment of Collective Health, Research Center for Major Themes, University of Brasília-
Autor(es): dc.contributorUniversity of Brasília, Central Institute of Sciences, Research Center for Major Themes-
Autor(es): dc.creatorAlmeida, Ricardo Titze de-
Autor(es): dc.creatorCunha, Thaylise Ramalho da-
Autor(es): dc.creatorSilva, Letícia Dias dos Santos-
Autor(es): dc.creatorFerreira, Clarisse Santos-
Autor(es): dc.creatorSilva, Caroline Pena-
Autor(es): dc.creatorRibeiro, Adriana Pinheiro-
Autor(es): dc.creatorSantos Júnior, Agenor de Castro Moreira-
Autor(es): dc.creatorBrandão, Pedro Renato de Paula-
Autor(es): dc.creatorSilva, Andrezza Paula Brito-
Autor(es): dc.creatorRocha, Márcia Cristina Oliveira da-
Autor(es): dc.creatorXavier, Mary‑Ann Elvina-
Autor(es): dc.creatorAlmeida, Simoneide Souza Titze de-
Autor(es): dc.creatorShimizu, Helena Eri-
Autor(es): dc.creatorRodrigues, Raimundo Nonato Delgado-
Data de aceite: dc.date.accessioned2024-10-23T15:04:19Z-
Data de disponibilização: dc.date.available2024-10-23T15:04:19Z-
Data de envio: dc.date.issued2024-07-04-
Data de envio: dc.date.issued2024-07-04-
Data de envio: dc.date.issued2022-02-07-
Fonte completa do material: dc.identifierhttp://repositorio2.unb.br/jspui/handle/10482/48547-
Fonte completa do material: dc.identifierhttps://doi.org/10.1186/s12879-022-07065-3-
Fonte completa do material: dc.identifierhttps://orcid.org/0000-0002-5019-4742-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/873539-
Descrição: dc.descriptionBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections lead to acute- and chronic Long COVID (LC) symptoms. However, few studies have addressed LC sequelae on brain functions. This study was aimed to examine if acute symptoms of coronavirus disease 2019 (COVID-19) would persist during LC, and if memory problems would be correlated with sleep, depressive mood, or anxious complaints. Methods: Our work followed a cohort of 236 patients from two public hospitals of the Federal District in mid-west‑ern Brazil. Patients’ interviews checked for clinical symptoms during acute and LC (5–8 months after real-time reverse transcription polymerase chain reaction, RT-qPCR). Results: Most cases were non-hospitalized individuals (86.3%) with a median age of 41.2 years. While myalgia (50%), hyposmia (48.3%), and dysgeusia (45.8%) were prevalent symptoms in acute phase, fatigue (21.6%) followed by headache (19.1%) and myalgia (16.1%) commonly occurred during LC. In LC, 39.8% of individuals reported memory complaints, 36.9% felt anxious, 44.9% felt depressed, and 45.8% had sleep problems. Furthermore, memory complaints were associated with sleep problems (adjusted OR 3.206; 95% CI 1.723–6.030) and depressive feelings (adjusted OR 3.981; 95% CI 2.068–7.815). Conclusions: The SARS-CoV-2 infection leads to persistent symptoms during LC, in which memory problems may be associated with sleep and depressive complaints.-
Descrição: dc.descriptionFaculdade de Agronomia e Medicina Veterinária (FAV)-
Descrição: dc.descriptionFaculdade de Ciências da Saúde (FS)-
Descrição: dc.descriptionDepartamento de Saúde Coletiva (FS DSC)-
Descrição: dc.descriptionInstituto de Ciências Biológicas (IB)-
Descrição: dc.descriptionFaculdade de Medicina (FM)-
Descrição: dc.descriptionPrograma de Pós-Graduação em Ciências da Saúde-
Descrição: dc.descriptionPrograma de Pós-Graduação em Nanociência e Nanobiotecnologia-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherBMC-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rights© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.-
Palavras-chave: dc.subjectMemória - aspectos fisiológicos-
Palavras-chave: dc.subjectDepressão mental-
Palavras-chave: dc.subjectSono - qualidade-
Palavras-chave: dc.subjectSaúde mental-
Palavras-chave: dc.subjectCovid-19-
Título: dc.titlePersistent, new‑onset symptoms and mental health complaints in Long COVID in a Brazilian cohort of non‑hospitalized patients-
Tipo de arquivo: dc.typelivro digital-
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