Atenção: Todas as denúncias são sigilosas e sua identidade será preservada.
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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | EORTC Quality of Life Group, Head and Neck Tumors, Brussels, Belgium | - |
Autor(es): dc.contributor | Brasília University, Radiation therapy Department | - |
Autor(es): dc.contributor | Brasília University, Radiation therapy Department | - |
Autor(es): dc.contributor | AC Camargo Cancer Center–São Paulo | - |
Autor(es): dc.contributor | Hospital Heliópolis, São Paulo | - |
Autor(es): dc.contributor | Prevent Sênior, São Paulo | - |
Autor(es): dc.contributor | Brasília University, Radiation therapy Department | - |
Autor(es): dc.contributor | Prevent Sênior, São Paulo | - |
Autor(es): dc.contributor | University of Campinas, Oncology Department | - |
Autor(es): dc.contributor | University of Campinas, Oncology Department | - |
Autor(es): dc.contributor | Santa Casa de Bagé | - |
Autor(es): dc.contributor | Pontifícia Universidade Católica, Porto Alegre, Radiation therapy Department | - |
Autor(es): dc.contributor | Hospital Geral de Caxias do Sul | - |
Autor(es): dc.contributor | Oncobeda, Centro Integrado de Oncologia, Campos, RJ | - |
Autor(es): dc.contributor | Brasília University, Radiation therapy Department | - |
Autor(es): dc.contributor | Hospital Bruno Born, Lajeado, RS, Brazil | - |
Autor(es): dc.contributor | Brasília University, Radiation therapy Department | - |
Autor(es): dc.contributor | Société Franco-Brésilienne de Cancérologie, Nice, France | - |
Autor(es): dc.contributor | AC Camargo Cancer Center–São Paulo | - |
Autor(es): dc.creator | Santos, Marcos | - |
Autor(es): dc.creator | Silva, Luís Felipe Oliveira e | - |
Autor(es): dc.creator | Kohler, Hugo F. | - |
Autor(es): dc.creator | Curioni, Otavio | - |
Autor(es): dc.creator | Vilela, Ricardo | - |
Autor(es): dc.creator | Fang, Marcel | - |
Autor(es): dc.creator | Lima, Carmen Silvia Passos | - |
Autor(es): dc.creator | Gomes, João Pedro | - |
Autor(es): dc.creator | Chaves, Aline | - |
Autor(es): dc.creator | Resende, Bruno | - |
Autor(es): dc.creator | Trindade, Karine | - |
Autor(es): dc.creator | Collares, Mauricio | - |
Autor(es): dc.creator | Obs, Fernando | - |
Autor(es): dc.creator | Brollo, Janaina | - |
Autor(es): dc.creator | Cavalieri, Ronaldo | - |
Autor(es): dc.creator | Ferreira, Ediane | - |
Autor(es): dc.creator | Brust, Leandro | - |
Autor(es): dc.creator | Ramos, Doralina do Amaral Rabello | - |
Autor(es): dc.creator | Domenge, Christian | - |
Autor(es): dc.creator | Kowalski, Luiz Paulo | - |
Data de aceite: dc.date.accessioned | 2024-07-22T12:54:11Z | - |
Data de disponibilização: dc.date.available | 2024-07-22T12:54:11Z | - |
Data de envio: dc.date.issued | 2023-10-09 | - |
Data de envio: dc.date.issued | 2023-10-09 | - |
Data de envio: dc.date.issued | 2020-09-21 | - |
Fonte completa do material: dc.identifier | http://repositorio2.unb.br/jspui/handle/10482/46640 | - |
Fonte completa do material: dc.identifier | https://doi.org/10.1016/j.ijrobp.2020.09.044 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/capes/813863 | - |
Descrição: dc.description | Purpose: To compare global health-related quality of life (HRQoL) and overall survival (OS) in patients with head and neck cancer treated with intensity modulated radiation therapy (IMRT), conformal radiation therapy (3DCRT) or conventional ra- diation therapy (2DRT). Methods and Materials: In this real-world, multi-institutional and prospective study, HRQoL outcomes were assessed using the European Organisation for Research and Treatment of Cancer Quality-of-life Questionnaire Core 30 (EORTC QLQ-C30) and European Organisation for Research and Treatment of Cancer Quality-of-life Questionnaire Head and Neck 43 (H&N43) questionnaires. Item response theory was used to generate a global HRQoL score, based on the 71 questions from both forms. The effect of treatment modality on HRQoL was studied using multivariate regression analyses. Survival was estimated using the Kaplan-Meyer method, and groups were compared by the log-rank test. Results: Five hundred and seventy patients from 13 institutions were included. Median follow-up was 12.2 months. Concern- ing the radiation technique, 29.5% of the patients were treated with 2DRT, 43.7% received 3DCRT, and 26.8% were treated with IMRT. A higher proportion of patients receiving 2DRT had a treatment interruption of more than 5 days (69% vs 50.2% for 3DCRT and 42.5% for IMRT). IMRT had a statistically significant positive effect on HRQoL compared with 3DCRT (bZ 2.627, standard error Z 0.804, P Z .001) and 2DRT had a statistically significant negative effect compared with 3DCRT (bZ 5.075, standard error Z 0.926, P < .001). Patients receiving 2DRT presented a worse OS (P Z .01). There were no differences in OS when IMRT was compared with 3DCRT. Conclusions: IMRT provided better HRQoL than 3DCRT, which provided better HRQoL than 2DRT. Patients receiving 2DRT presented a worse OS, which might be related to more frequent treatment interruptions. Ó 2020 Elsevier Inc. All rights reserved. | - |
Idioma: dc.language | en | - |
Publicador: dc.publisher | Elvsevier Inc. | - |
Relação: dc.relation | https://www.sciencedirect.com/science/article/pii/S0360301620343467?via%3Dihub | - |
Direitos: dc.rights | Acesso Restrito | - |
Palavras-chave: dc.subject | Qualidade de vida | - |
Palavras-chave: dc.subject | Saúde | - |
Palavras-chave: dc.subject | Cabeça - câncer | - |
Palavras-chave: dc.subject | Pescoço - câncer | - |
Palavras-chave: dc.subject | Radioterapia | - |
Título: dc.title | Health-related quality of life outcomes in head and neck cancer : results from a prospective, real-world data study with Brazilian patients treated with intensity modulated radiation therapy, conformal and conventional radiation techniques | - |
Aparece nas coleções: | Repositório Institucional – UNB |
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