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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.creator | Freitas, Pedro Felipe Silva de | - |
Autor(es): dc.creator | Durães, Leonardo de Castro | - |
Autor(es): dc.creator | Carvalho, Felipe Augusto Neves Oliveira de | - |
Autor(es): dc.creator | Duarte, Sérgio Andurte Carvalho | - |
Autor(es): dc.creator | Carneiro, Fabiana Pirani | - |
Autor(es): dc.creator | Sousa, João Batista de | - |
Data de aceite: dc.date.accessioned | 2024-07-22T12:32:36Z | - |
Data de disponibilização: dc.date.available | 2024-07-22T12:32:36Z | - |
Data de envio: dc.date.issued | 2017-12-07 | - |
Data de envio: dc.date.issued | 2017-12-07 | - |
Data de envio: dc.date.issued | 2013-07 | - |
Fonte completa do material: dc.identifier | http://repositorio.unb.br/handle/10482/28803 | - |
Fonte completa do material: dc.identifier | https://dx.doi.org/10.1590/S0102-86502013000700003 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/capes/806016 | - |
Descrição: dc.description | PURPOSE: To evaluate the effects of pneumoperitoneum with carbon dioxide and helium on renal function and morphology in a rat model. METHODS: Twenty four rats were randomized into three groups (n=8): gasless insufflation ('open', Pressure=0 mmHg), carbon dioxide pneumoperitoneum at 12 mmHg, and helium pneumoperitoneum at 12 mmHg; all lasting 90 minutes.. A cystostomy was performed and the bladder was emptied. At the end of the experiment, the urine produced, a blood sample and the left kidney of each animal were collected. The following variables were obtained: serum sodium, potassium, urea and creatinine, urine volume and creatinine. The creatinine clearance was estimated for each animal. The kidneys were stained with hematoxylin and eosin (HE) and evaluated by a pathologist blinded to the groups. RESULTS: The CO2 and Helium groups did not differ in the variables evaluated. Both developed oliguria (p<0.001 vs. gasless). The CO2 group presented hyperkalemia compared to gasless (p=0.05), which did not attain significance in the helium group. Histopathological analysis revealed mild hydropic degeneration and congestion in the three groups, with no significant difference among them. CONCLUSIONS: The type of gas resulted in no difference in the variables of renal function and morphology assessed. The increase in serum potassium was only observed with CO2 insufflation suggests a combined effect of elevated intra-abdominal pressure and metabolic effects of pneumoperitoneum. | - |
Descrição: dc.description | Faculdade de Medicina (FMD) | - |
Formato: dc.format | application/pdf | - |
Idioma: dc.language | en | - |
Publicador: dc.publisher | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia | - |
Direitos: dc.rights | Acesso Aberto | - |
Direitos: dc.rights | Acta Cirúrgica Brasileira - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License (CC BY NC 4.0). Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000700003&lng=en&tlng=en. Acesso em: 04 dez. 2020. | - |
Palavras-chave: dc.subject | Cirurgia | - |
Palavras-chave: dc.subject | Laparoscopia | - |
Palavras-chave: dc.subject | Pneumoperitônio | - |
Palavras-chave: dc.subject | Dióxido de carbono | - |
Palavras-chave: dc.subject | Rins | - |
Palavras-chave: dc.subject | Ratos | - |
Título: dc.title | Effects of pneumoperitoneum with carbon dioxide and helium on renal function and morphology in rats | - |
Aparece nas coleções: | Repositório Institucional – UNB |
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