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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group | - |
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group | - |
Autor(es): dc.contributor | Federal Institute of Education, Science and Technology Goiano, Ceres, GO | - |
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Department of Pharmacy | - |
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group | - |
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologies | - |
Autor(es): dc.contributor | LS Educational, Microbiology Laboratory, Brasilia, Brazil | - |
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Department of Pharmacy | - |
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologies | - |
Autor(es): dc.contributor | University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group | - |
Autor(es): dc.creator | Illanes Tormena, Renata Pascoal | - |
Autor(es): dc.creator | Rosa, Eliane Vieira | - |
Autor(es): dc.creator | Mota, Bruna de Fatima Oliveira | - |
Autor(es): dc.creator | Chaker, Juliano Alexandre | - |
Autor(es): dc.creator | Fagg, Christopher William | - |
Autor(es): dc.creator | Freire, Daniel Oliveira | - |
Autor(es): dc.creator | Martins, Paula Melo | - |
Autor(es): dc.creator | Silva, Izabel Cristina Rodrigues da | - |
Autor(es): dc.creator | Sousa, Marcelo Henrique | - |
Data de aceite: dc.date.accessioned | 2024-07-22T12:22:09Z | - |
Data de disponibilização: dc.date.available | 2024-07-22T12:22:09Z | - |
Data de envio: dc.date.issued | 2023-11-26 | - |
Data de envio: dc.date.issued | 2023-11-26 | - |
Data de envio: dc.date.issued | 2020-06-21 | - |
Fonte completa do material: dc.identifier | http://repositorio2.unb.br/jspui/handle/10482/46911 | - |
Fonte completa do material: dc.identifier | https://doi.org/10.1039/D0RA03240A | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-3248-1286 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-2144-0959 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-6072-7832 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-1210-8329 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/capes/802162 | - |
Descrição: dc.description | We describe here a green method for the preparation of silver nanoparticles (AgNPs), by a microwave assisted synthesis route using Handroanthus impetiginosus underbark extract, with antibacterial activity. After optimizing the synthesis parameters with a Box–Benhken designed experiment, samples were characterized by powder XRD, TEM, UV-Vis spectroscopy, FTIR and zetametry. Using the overall optimized conditions of synthesis – time of reaction 15 min at 200 C and plant extract/AgNO3 volume ratio equal to 10% – highly crystalline 13.4 nm-sized spherical AgNPs in a well-dispersed colloidal state were obtained. It was also proved that the plant extract compounds act as reductant and capping agents during synthesis to functionalize AgNPs, resulting in a negatively charged surface with high values of zeta potential in a wide range of pH, from acidic to alkaline media. Biological activity tests against Staphylococcus aureus and Escherichia coli and cell viability experiments showed that synthesized AgNPs were not toxic to HaCaT mammalian cells and presented a high efficiency against Gram-positive bacteria (S. aureus). This was associated with the synergistic combination of AgNP silver cores with the capping layer containing natural compounds with antimicrobial properties and considered an alternative to the AgNPs commonly obtained from conventional routes that present antibacterial effectiveness preferentially against Gram-negative strains. | - |
Descrição: dc.description | Faculdade UnB Ceilândia (FCE) | - |
Descrição: dc.description | Curso de Farmácia (FCE-FAR) | - |
Descrição: dc.description | Programa de Pós-Graduação em Ciências e Tecnologias em Saúde | - |
Formato: dc.format | application/pdf | - |
Idioma: dc.language | en | - |
Publicador: dc.publisher | The Royal Society of Chemistry | - |
Direitos: dc.rights | Acesso Aberto | - |
Direitos: dc.rights | (CC BY-NC). This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence | - |
Palavras-chave: dc.subject | Atividade antimicrobiana | - |
Palavras-chave: dc.subject | Nanopartículas de prata | - |
Palavras-chave: dc.subject | Ipê roxo | - |
Título: dc.title | Evaluation of the antimicrobial activity of silver nanoparticles obtained by microwave-assisted green synthesis using Handroanthus impetiginosus (Mart. ex DC.) Mattos underbark extract | - |
Aparece nas coleções: | Repositório Institucional – UNB |
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