Engineering gold shelled nanomagnets for pre-setting the operating temperature for magnetic hyperthermia

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Autor(es): dc.contributorUniversity of Brasília, Institute of Biological Sciences, Department of Genetics & Morphology-
Autor(es): dc.contributorUniversity of Brasília, Faculty of Ceilândia, Green Nanotechnology Group-
Autor(es): dc.contributorUniversity of Brasília, Faculty of Ceilândia, Post-Graduation Program in Sciences and Health Technologies-
Autor(es): dc.contributorFederal University of Goiás, Institute of Physics-
Autor(es): dc.contributorUniversity of Brasília, Institute of Physics-
Autor(es): dc.contributorFederal Institute of Brasília-
Autor(es): dc.contributorFederal University of Goiás, Institute of Physics-
Autor(es): dc.contributorFederal University of Goiás, CNanoMed-
Autor(es): dc.contributorUniversity of Brasília, Institute of Biological Sciences, Department of Genetics & Morphology-
Autor(es): dc.contributorUniversity of Brasília, Faculty of Ceilândia, Green Nanotechnology Group-
Autor(es): dc.contributorUniversity of Brasília, Faculty of Ceilândia, Post-Graduation Program in Sciences and Health Technologies-
Autor(es): dc.contributorUniversity of Brasília, Institute of Physics-
Autor(es): dc.contributorCatholic University of Brasília-
Autor(es): dc.creatorSiqueira, Elis Regina Lima-
Autor(es): dc.creatorPinheiro, Willie Oliveira-
Autor(es): dc.creatorAquino, Victor Raul Romero-
Autor(es): dc.creatorCoelho, Breno Cunha Pinto-
Autor(es): dc.creatorBakuzis, Andris Figueiroa-
Autor(es): dc.creatorAzevedo, Ricardo Bentes-
Autor(es): dc.creatorSousa, Marcelo Henrique-
Autor(es): dc.creatorMorais, Paulo Cesar-
Data de aceite: dc.date.accessioned2024-07-22T11:35:55Z-
Data de disponibilização: dc.date.available2024-07-22T11:35:55Z-
Data de envio: dc.date.issued2024-07-11-
Data de envio: dc.date.issued2024-07-11-
Data de envio: dc.date.issued2022-08-12-
Fonte completa do material: dc.identifierhttp://repositorio2.unb.br/jspui/handle/10482/48763-
Fonte completa do material: dc.identifierhttps://doi.org/10.3390/nano12162760 10.3390/nano12162760-
Fonte completa do material: dc.identifierhttps://orcid.org/0000-0003-3366-106X-
Fonte completa do material: dc.identifierhttps://orcid.org/0000-0002-2137-9588-
Fonte completa do material: dc.identifierhttps://orcid.org/0000-0003-1210-8329-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/784362-
Descrição: dc.descriptionThis study investigated the fabrication of spherical gold shelled maghemite nanoparticles for use in magnetic hyperthermia (MHT) assays. A maghemite core (14 ± 3 nm) was used to fabricate two samples with different gold thicknesses, which presented gold (g)/maghemite (m) content ratios of 0.0376 and 0.0752. The samples were tested in MHT assays (temperature versus time) with varying frequencies (100–650 kHz) and field amplitudes (9–25 mT). The asymptotic temperatures (T∞) of the aqueous suspensions (40 mg Fe/mL) were found to be in the range of 59–77 ◦C (naked maghemite), 44–58 ◦C (g/m = 0.0376) and 33–51 ◦C (g/m = 0.0752). The MHT data revealed that T∞ could be successful controlled using the gold thickness and cover the range for cell apoptosis, thereby providing a new strategy for the safe use of MHT in practice. The highest SAR (specific absorption rate) value was achieved (75 kW/kg) using the thinner gold shell layer (334 kHz, 17 mT) and was roughly twenty times bigger than the best SAR value that has been reported for similar structures. Moreover, the time that was required to achieve T∞ could be modeled by changing the thermal conductivity of the shell layer and/or the shape/size of the structure. The MHT assays were pioneeringly modeled using a derived equation that was analytically identical to the Box–Lucas method (which was reported as phenomenological).-
Descrição: dc.descriptionInstituto de Ciências Biológicas (IB)-
Descrição: dc.descriptionDepartamento de Genética e Morfologia (IB GEM)-
Descrição: dc.descriptionFaculdade UnB Ceilândia (FCE)-
Descrição: dc.descriptionInstituto de Física (IF)-
Descrição: dc.descriptionPrograma de Pós-Graduação em Ciências e Tecnologias em Saúde-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherMDPI-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rights© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).-
Palavras-chave: dc.subjectMagnetohipertermia-
Palavras-chave: dc.subjectNanopartículas magnéticas-
Palavras-chave: dc.subjectFluidos magnéticos-
Palavras-chave: dc.subjectTemperatura-
Título: dc.titleEngineering gold shelled nanomagnets for pre-setting the operating temperature for magnetic hyperthermia-
Aparece nas coleções:Repositório Institucional – UNB

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