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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.creator | Ferreira, Juliana de Freitas | - |
Autor(es): dc.creator | Mera López, Manuel Humberto | - |
Autor(es): dc.creator | Gomes, João Victor Dutra | - |
Autor(es): dc.creator | Martins, Diegue Henrique Nascimento | - |
Autor(es): dc.creator | Fagg, Christopher William | - |
Autor(es): dc.creator | Batista, Pérola de Oliveira Magalhães Dias | - |
Autor(es): dc.creator | Davies, Noel William | - |
Autor(es): dc.creator | Silveira, Dâmaris | - |
Autor(es): dc.creator | Bazzo, Yris Maria Fonseca | - |
Data de aceite: dc.date.accessioned | 2024-07-22T11:35:12Z | - |
Data de disponibilização: dc.date.available | 2024-07-22T11:35:12Z | - |
Data de envio: dc.date.issued | 2022-05-05 | - |
Data de envio: dc.date.issued | 2022-05-05 | - |
Data de envio: dc.date.issued | 2021 | - |
Fonte completa do material: dc.identifier | https://repositorio.unb.br/handle/10482/43650 | - |
Fonte completa do material: dc.identifier | https://doi.org/10.3390/molecules27031120 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-8727-0043 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-6098-3852 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-6072-7832 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0001-8011-6940 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0003-1851-5224 | - |
Fonte completa do material: dc.identifier | https://orcid.org/0000-0002-1230-3207 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/capes/784066 | - |
Descrição: dc.description | Miconia chamissois Naudin is a species from the Cerrado, which is being increasingly researched for its therapeutic potential. The aim of this study was to obtain a standardized extract and to evaluate seasonal chemical variations. Seven batches of aqueous extracts from leaves were produced for the standardization. These extracts were evaluated for total solids, polyphenol (TPC) and flavonoid content (TFC), vitexin derivative content, antioxidant activity; thin-layer chromatography (TLC), and high-performance liquid chromatography (HPLC) profiles were generated. For the seasonal study, leaves were collected from five different periods (May 2017 to August 2018). The results were correlated with meteorological data (global radiation, temperature, and rainfall index). Using chromatographic and spectroscopic techniques, apigenin C-glycosides (vitexin/isovitexin) and derivatives, luteolin C-glycosides (orientin/isoorientin) and derivatives, a quercetin glycoside, miconioside B, matteucinol-7-O-β-apiofuranosyl (1 → 6) -β-glucopyranoside, and farrerol were identified. Quality parameters, including chemical marker quantification by HPLC, and biological activity, are described. In the extract standardization process, all the evaluated parameters showed low variability. The seasonality study revealed no significant correlations (p < 0.05) between TPC or TFC content and meteorological data. These results showed that it is possible to obtain extracts from M. chamissois at any time of the year without significant differences in composition. | - |
Formato: dc.format | application/pdf | - |
Publicador: dc.publisher | MDPI | - |
Direitos: dc.rights | Acesso Aberto | - |
Direitos: dc.rights | (CC BY) | - |
Palavras-chave: dc.subject | Miconia chamissois | - |
Palavras-chave: dc.subject | Sazonalidade | - |
Palavras-chave: dc.subject | Cerrados | - |
Título: dc.title | Seasonal chemical evaluation of Miconia chamissois Naudin from Brazilian Savanna | - |
Aparece nas coleções: | Repositório Institucional – UNB |
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