Evidence of association between the use of drugs and community-dwelling older people frailty : a cross-sectional study

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Autor(es): dc.creatorAlves, Marcos Kaic Lopes-
Autor(es): dc.creatorOliveira, Nayara Gomes Nunes-
Autor(es): dc.creatorPegorari, Maycon Sousa-
Autor(es): dc.creatorTavares, Darlene Mara dos Santos-
Autor(es): dc.creatorRodrigues, Maria Cristina Soares-
Autor(es): dc.creatorBolina, Alisson Fernandes-
Data de aceite: dc.date.accessioned2021-10-14T18:34:40Z-
Data de disponibilização: dc.date.available2021-10-14T18:34:40Z-
Data de envio: dc.date.issued2021-05-12-
Data de envio: dc.date.issued2021-05-12-
Data de envio: dc.date.issued2020-11-
Fonte completa do material: dc.identifierhttps://repositorio.unb.br/handle/10482/40913-
Fonte completa do material: dc.identifierhttps://doi.org/10.1590/1516-3180.2020.0205.r1.06082020-
Fonte completa do material: dc.identifierhttp://orcid.org/0000-0003-0808-300X-
Fonte completa do material: dc.identifierhttp://orcid.org/0000-0003-4170-8761-
Fonte completa do material: dc.identifierhttp://orcid.org/0000-0003-4015-9895-
Fonte completa do material: dc.identifierhttp://orcid.org/0000-0001-9565-0476-
Fonte completa do material: dc.identifierhttp://orcid.org/0000-0003-0206-4238-
Fonte completa do material: dc.identifierhttp://orcid.org/0000-0002-1364-0176-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/634955-
Descrição: dc.descriptionBACKGROUND: The scientific literature has shown that an association between polypharmacy and frailty exists. However, few studies have also considered drug interactions and the use of potentially inappropriate medications. OBJECTIVE: To evaluate the association between the use of drugs and frailty among community-dwelling older people. DESIGN AND SETTING: Cross-sectional study carried out among 580 older people in Uberaba (MG). METHODS: Data were collected at these older people's homes using instruments validated in Brazil. Descriptive, bivariate and binary logistic regression analyses were performed (P < 0.05). RESULTS: Most of these individuals were classified as pre-frail (55.7%), while 13.1% were frail. It was found that 31.7% of them presented polypharmacy, 41.7% had drug interactions and 43.8% were using potentially inappropriate medications. In the initial model, polypharmacy (odds ratio, OR = 1.91; confidence interval, CI = 1.27-2.86) and use of potentially inappropriate medications (OR = 2.45; CI = 1.68-3.57) increased the chance that these older people would be pre-frail or frail. In the final adjusted model, use of potentially inappropriate drugs remained associated with the outcome (OR = 2.26; CI = 1.43-3.57). CONCLUSION: Use of potentially inappropriate medications was the independent variable that explained the occurrence of frailty in a representative sample of community-dwelling older adults.-
Formato: dc.formatapplication/pdf-
Publicador: dc.publisherAssociação Paulista de Medicina - APM-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rightsCC BY. This is an open access article distributed under the terms of the Creative Commons license. © 2020 by Associação Paulista de Medicina.-
Palavras-chave: dc.subjectPolifarmácia-
Palavras-chave: dc.subjectMedicamentos - interações-
Palavras-chave: dc.subjectIdosos-
Título: dc.titleEvidence of association between the use of drugs and community-dwelling older people frailty : a cross-sectional study-
Tipo de arquivo: dc.typelivro digital-
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