Effects of pneumoperitoneum with carbon dioxide and helium on renal function and morphology in rats

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Autor(es): dc.creatorFreitas, Pedro Felipe Silva de-
Autor(es): dc.creatorDurães, Leonardo de Castro-
Autor(es): dc.creatorCarvalho, Felipe Augusto Neves Oliveira de-
Autor(es): dc.creatorDuarte, Sérgio Andurte Carvalho-
Autor(es): dc.creatorCarneiro, Fabiana Pirani-
Autor(es): dc.creatorSousa, João Batista de-
Data de aceite: dc.date.accessioned2021-10-14T18:16:19Z-
Data de disponibilização: dc.date.available2021-10-14T18:16:19Z-
Data de envio: dc.date.issued2017-12-07-
Data de envio: dc.date.issued2017-12-07-
Data de envio: dc.date.issued2013-07-
Fonte completa do material: dc.identifierhttp://repositorio.unb.br/handle/10482/28803-
Fonte completa do material: dc.identifierhttps://dx.doi.org/10.1590/S0102-86502013000700003-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/627598-
Descrição: dc.descriptionPURPOSE: To evaluate the effects of pneumoperitoneum with carbon dioxide and helium on renal function and morphology in a rat model. METHODS: Twenty four rats were randomized into three groups (n=8): gasless insufflation ('open', Pressure=0 mmHg), carbon dioxide pneumoperitoneum at 12 mmHg, and helium pneumoperitoneum at 12 mmHg; all lasting 90 minutes.. A cystostomy was performed and the bladder was emptied. At the end of the experiment, the urine produced, a blood sample and the left kidney of each animal were collected. The following variables were obtained: serum sodium, potassium, urea and creatinine, urine volume and creatinine. The creatinine clearance was estimated for each animal. The kidneys were stained with hematoxylin and eosin (HE) and evaluated by a pathologist blinded to the groups. RESULTS: The CO2 and Helium groups did not differ in the variables evaluated. Both developed oliguria (p<0.001 vs. gasless). The CO2 group presented hyperkalemia compared to gasless (p=0.05), which did not attain significance in the helium group. Histopathological analysis revealed mild hydropic degeneration and congestion in the three groups, with no significant difference among them. CONCLUSIONS: The type of gas resulted in no difference in the variables of renal function and morphology assessed. The increase in serum potassium was only observed with CO2 insufflation suggests a combined effect of elevated intra-abdominal pressure and metabolic effects of pneumoperitoneum.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia-
Direitos: dc.rightsAcesso Aberto-
Direitos: dc.rightsActa Cirúrgica Brasileira - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License (CC BY NC 4.0). Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000700003&lng=en&tlng=en. Acesso em: 04 dez. 2020.-
Palavras-chave: dc.subjectCirurgia-
Palavras-chave: dc.subjectLaparoscopia-
Palavras-chave: dc.subjectPneumoperitônio-
Palavras-chave: dc.subjectDióxido de carbono-
Palavras-chave: dc.subjectRins-
Palavras-chave: dc.subjectRatos-
Título: dc.titleEffects of pneumoperitoneum with carbon dioxide and helium on renal function and morphology in rats-
Tipo de arquivo: dc.typelivro digital-
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