Cardiac and renal effects induced by different exercise workloads in renovascular hypertensive rats.

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Autor(es): dc.creatorSoares, Everton Rocha-
Autor(es): dc.creatorLima, Wanderson Geraldo de-
Autor(es): dc.creatorMachado, Raquel do Pilar-
Autor(es): dc.creatorCarneiro, Cláudia Martins-
Autor(es): dc.creatorSilva, Marcelo Eustáquio-
Autor(es): dc.creatorBarbosa, Miriam Carmo Rodrigues-
Autor(es): dc.creatorCastro, Uberdan Guilherme Mendes de-
Autor(es): dc.creatorSantos, Robson Augusto Souza dos-
Autor(es): dc.creatorSantos, Maria José Campagnole dos-
Autor(es): dc.creatorAlzamora, Andréia Carvalho-
Data de aceite: dc.date.accessioned2019-11-06T13:36:14Z-
Data de disponibilização: dc.date.available2019-11-06T13:36:14Z-
Data de envio: dc.date.issued2016-01-18-
Data de envio: dc.date.issued2016-01-18-
Data de envio: dc.date.issued2011-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/handle/123456789/6100-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/559175-
Descrição: dc.descriptionWe examined the effect of exercise training (Ex) without (Ex 0%) or with a 3% workload (Ex 3%) on different cardiac and renal parameters in renovascular hypertensive (2K1C) male Fisher rats weighing 150-200 g. Ex was performed for 5 weeks, 1 h/day, 5 days/week. Ex 0% or Ex 3% induced similar attenuation of baseline mean arterial pressure (MAP, 119 ± 5 mmHg in 2K1C Ex 0%, N = 6, and 118 ± 5 mmHg in 2K1C Ex 3%, N = 11, vs 99 ± 4 mmHg in sham sedentary (Sham Sed) controls, N = 10) and heart rate (HR, bpm) (383 ± 13 in 2K1C Ex 0%, N = 6, and 390 ± 14 in 2K1C Ex 3%, N = 11 vs 371 ± 11 in Sham Sed, N = 10). Ex 0%, but not Ex 3%, improved baroreflex bradycardia (0.26 ± 0.06 ms/mmHg, N = 6, vs 0.09 ± 0.03 ms/mmHg in 2K1C Sed, N = 11). Morphometric evaluation suggested concentric left ventricle hypertrophy in sedentary 2K1C rats. Ex 0% prevented concentric cardiac hypertrophy, increased cardiomyocyte diameter and decreased cardiac vasculature thickness in 2K1C rats. In contrast, in 2K1C, Ex 3% reduced the concentric remodeling and prevented the increase in cardiac vasculature wall thickness, decreased the cardiomyocyte diameter and increased collagen deposition. Renal morphometric analysis showed that Ex 3% induced an increase in vasculature wall thickness and collagen deposition in the left kidney of 2K1C rats. These data suggest that Ex 0% has more beneficial effects than Ex 3% in renovascular hypertensive rats.-
Idioma: dc.languageen-
Direitos: dc.rightsTodo o conteúdo do periódico Brazilian journal of medical and biological research, exceto onde identificado, está licenciado sob uma licença Creative Commons que permite copiar, distribuir e transmitir o trabalho em qualquer suporte ou formato desde que sejam citados o autor e o licenciante. Fonte: <http://www.scielo.br/scielo.php?script=sci_serial&pid=0100-879X&lng=en&nrm=iso>. Acesso em: 21 out. 2015.-
Palavras-chave: dc.subjectBaroreflex bradycardia-
Palavras-chave: dc.subjectRenovascular hypertension-
Título: dc.titleCardiac and renal effects induced by different exercise workloads in renovascular hypertensive rats.-
Aparece nas coleções:Repositório Institucional - UFOP

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