Malnutrition enhances cardiovascular responses to chemoreflex activation in awake rats

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorPenitente, Arlete Rita-
Autor(es): dc.creatorFernandes, Luciano Gonçalves-
Autor(es): dc.creatorCardoso, Leonardo Máximo-
Autor(es): dc.creatorSilva, Marcelo Eustáquio-
Autor(es): dc.creatorPedrosa, Maria Lúcia-
Autor(es): dc.creatorSilva, Antônio Leite-
Autor(es): dc.creatorHaibara, Andréa Siqueira-
Autor(es): dc.creatorMoraes, Márcio Flávio Dutra-
Autor(es): dc.creatorChianca Júnior, Deoclécio Alves-
Data de aceite: dc.date.accessioned2019-11-06T13:25:36Z-
Data de disponibilização: dc.date.available2019-11-06T13:25:36Z-
Data de envio: dc.date.issued2012-11-26-
Data de envio: dc.date.issued2012-11-26-
Data de envio: dc.date.issued2007-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/123456789/1807-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/555124-
Descrição: dc.descriptionSeveral studies in the literature suggest that low-protein intake is associated with increases in sympathetic efferent activity and cardiovascular disease. Among the possible mechanisms, changes in the neurotransmission of cardiovascular reflexes have been implicated. Therefore, the present study comprised the evaluation of chemoreflex responsiveness in rats subjected to a low-protein diet during the 35 days after weaning. As a result, we observed that malnourished rats presented higher levels of baseline mean arterial pressure and heart rate and exhibited a mild increase in the pressor response to chemoreflex activation. They also exhibited a massive bradycardic response to chemoreflex activation. Interestingly, bilateral ligature of the carotid body arteries further increased baseline mean arterial pressure and heart rate in malnourished animals. The data suggest severe autonomic imbalance and/or change in the central interplay between neural and cardiovascular mechanisms.-
Idioma: dc.languageen-
Direitos: dc.rightsO Periódico Life Sciences concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3314370163366-
Palavras-chave: dc.subjectAlbumin-
Palavras-chave: dc.subjectLow-protein diet-
Palavras-chave: dc.subjectSympathetic activity-
Palavras-chave: dc.subjectArterial pressure-
Palavras-chave: dc.subjectChemoreflex-
Título: dc.titleMalnutrition enhances cardiovascular responses to chemoreflex activation in awake rats-
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