Susceptibility to re-infection in C57BL/6 mice with recombinant strains of Toxoplasma gondii.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorBrandão, Geane Peroni-
Autor(es): dc.creatorMelo, Maria Norma-
Autor(es): dc.creatorCaetano, Bráulia Costa-
Autor(es): dc.creatorCarneiro, Cláudia Martins-
Autor(es): dc.creatorSilva, Letícia de Azevedo-
Autor(es): dc.creatorVitor, Ricardo Wagner de Almeida-
Data de aceite: dc.date.accessioned2019-11-06T13:24:58Z-
Data de disponibilização: dc.date.available2019-11-06T13:24:58Z-
Data de envio: dc.date.issued2012-09-11-
Data de envio: dc.date.issued2012-09-11-
Data de envio: dc.date.issued2011-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/123456789/1382-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/554917-
Descrição: dc.descriptionThis work reports results of re-infection of BALB/c and C57BL/6 mice with different recombinant strains of Toxoplasma gondii. Mice were prime-infected with the non-virulent D8 strain and challenged with virulent strains. PCR–RFLP of cS10-A6 genetic marker of T. gondii demonstrated that BALB/c mice were reinfected with the EGS strain, while C57BL/6 mice were re-infected with the EGS and CH3 strains. Levels of IFN-c and IL-10 after D8 prime-infection were lower in C57BL/6 than in BALB/c mice. Brain inflammation after D8 prime-infection was more intense in C57BL/6 than in BALB/c mice. It was shown that reinfection depends on mice lineage and genotype of the strain used in the challenge.-
Idioma: dc.languageen-
Direitos: dc.rightsO Periódico Experimental Parasitology concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3280861265494-
Palavras-chave: dc.subjectExperimental toxoplasmosis-
Palavras-chave: dc.subjectRe-infection-
Palavras-chave: dc.subjectRecombinant strains-
Palavras-chave: dc.subjectC57BL/6-
Palavras-chave: dc.subjectBALB/c-
Título: dc.titleSusceptibility to re-infection in C57BL/6 mice with recombinant strains of Toxoplasma gondii.-
Aparece nas coleções:Repositório Institucional - UFOP

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