Antinociceptive and anti-inflammatory activities of ethanolic extracts of Lychnophora species.

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorGuzzo, Luciana Souza-
Autor(es): dc.creatorGuimarães, Dênia Antunes Saúde-
Autor(es): dc.creatorSilva, Adriana Carneiro-
Autor(es): dc.creatorLombardi, Júlio Antônio-
Autor(es): dc.creatorGuimarães, Homero Nogueira-
Autor(es): dc.creatorGuimarães, Andrea Grabe-
Data de aceite: dc.date.accessioned2019-11-06T13:24:16Z-
Data de disponibilização: dc.date.available2019-11-06T13:24:16Z-
Data de envio: dc.date.issued2012-07-10-
Data de envio: dc.date.issued2012-07-10-
Data de envio: dc.date.issued2008-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/123456789/1057-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/554671-
Descrição: dc.descriptionExtracts from Lychnophora species are traditionally used in Brazil as anti-inflammatory, and to treat bruise, pain and rheumatism. The ethanolic extract of aerial parts of five species of Lychnophoras and one specie of Lychnophoriopsis were examined for the antinociceptive (hot-plate and writhing tests) and anti-inflammatory (carrageenan-induced paw oedema test) activity in mice, by oral and topical routes, respectively. In the hot-plate test, the Lychnophora pinaster (0.75 g/kg) and Lychnophora ericoides (1.50 g/kg) extracts significantly increased the time for licking of the paws. The species Lychnophora passerina, Lychnophoriopsis candelabrum and Lychnophora pinaster, using the dose of 0.75 g/kg, and Lychnophora ericoides and Lychnophora trichocarpha in both doses evaluated (0.75 and 1.50 g/kg) significantly reduced the number of writhes induced by acetic acid. The administration of Lychnophora pinaster and Lychnophora trichocarpha ointments, in both concentrations evaluated (5 and 10%, w/w), and Lychnophora passerina and Lychnophoriopsis candelabrum, in the concentration of 10%, significantly reduced the paw oedema measured 3 h after carrageenan administration, suggesting, for the first time, an anti-inflammatory activity upon topical administration of these species. The present work comparatively demonstrated the antinociceptive and anti-inflammatory activities of some Brazilian Lychnophoras.-
Idioma: dc.languageen-
Direitos: dc.rightsO Periódico Journal of Ethnopharmacology concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 494627212.-
Palavras-chave: dc.subjectAntinociceptive activity-
Palavras-chave: dc.subjectWrithing test-
Palavras-chave: dc.subjectLychnophoras-
Palavras-chave: dc.subjectAnti-inflammatory activity-
Palavras-chave: dc.subjectCarrageenan-
Palavras-chave: dc.subjectHot-plate test-
Título: dc.titleAntinociceptive and anti-inflammatory activities of ethanolic extracts of Lychnophora species.-
Aparece nas coleções:Repositório Institucional - UFOP

Não existem arquivos associados a este item.