Histopathological and immunohistochemical investigations of the hepatic compartment associated with parasitism and serum biochemical changes in canine visceral leishmaniasis.

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorGiunchetti, Rodolfo Cordeiro-
Autor(es): dc.creatorMayrink, Wilson-
Autor(es): dc.creatorCarneiro, Cláudia Martins-
Autor(es): dc.creatorOliveira, Rodrigo Corrêa de-
Autor(es): dc.creatorMartins Filho, Olindo Assis-
Autor(es): dc.creatorMarques, Marcos José-
Autor(es): dc.creatorTafuri, Wagner Luiz-
Autor(es): dc.creatorReis, Alexandre Barbosa-
Data de aceite: dc.date.accessioned2019-11-06T13:24:09Z-
Data de disponibilização: dc.date.available2019-11-06T13:24:09Z-
Data de envio: dc.date.issued2012-07-05-
Data de envio: dc.date.issued2012-07-05-
Data de envio: dc.date.issued2008-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/123456789/972-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/554627-
Descrição: dc.descriptionThe immunopathological evaluation of the hepatic compartment associated with parasitism and biochemical findings are essential for understanding the genesis of hepatomegaly in anine visceral leishmaniasis (CVL). Three clinical groups of dogs naturally infected with Leishmania chagasi[i.e., asymptomatic (AD, n = 12), oligosymptomatic (OD,n = 12) and symptomatic (SD,n = 17)] were assessed and compared with a group of non-infected dogs (NID,n = 11). Intense reaction of the Kupffer cells, capsule and portal inflammation, and the presence of intralobular granulomas, were observed in the different clinical groups. Dogs in the SD group presented a higher frequency of parasitism compared with the AD group. Inflammatory alterations were more intense in the SD group and were associated with parasit-ism. Our results indicated an association between histological liver changes and the progression of biochemical alterations according to pro-gression of clinical forms of CVL, and the direct relationship between clinical symptoms and frequency of hepatic parasitism.-
Idioma: dc.languageen-
Direitos: dc.rightsO Periódico Research in Veterinary Science concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3281420662301-
Palavras-chave: dc.subjectDog-
Palavras-chave: dc.subjectHistopathology-
Palavras-chave: dc.subjectImmunohistochemistry-
Palavras-chave: dc.subjectLDU index-
Palavras-chave: dc.subjectLeishmania chagasi-
Palavras-chave: dc.subjectLiver-
Palavras-chave: dc.subjectParasitism-
Palavras-chave: dc.subjectVisceral leishmaniasis-
Título: dc.titleHistopathological and immunohistochemical investigations of the hepatic compartment associated with parasitism and serum biochemical changes in canine visceral leishmaniasis.-
Aparece nas coleções:Repositório Institucional - UFOP

Não existem arquivos associados a este item.