A moving myosin motor protein

Registro completo de metadados
Autor(es): dc.creatorVale, Ronald D.-
Autor(es): dc.creatorMilligan, Ronald A.-
Data de aceite: dc.date.accessioned2019-08-21T19:26:07Z-
Data de disponibilização: dc.date.available2019-08-21T19:26:07Z-
Data de envio: dc.date.issued2006-08-
Data de envio: dc.date.issued2009-06-05-
Data de envio: dc.date.issued2012-12-04-
Data de envio: dc.date.issued2012-12-04-
Data de envio: dc.date.issued2012-12-04-
Fonte completa do material: dc.identifierhttp://objetoseducacionais2.mec.gov.br/handle/mec/22169-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/491936-
Descrição: dc.descriptionThe muscle myosin is a dimer of two identical motor heads (catalytic cores are blue; lever arms in the prestroke ADP-Pi state are yellow), which are anchored to the thick filament (top) by a coiled coil (gray rod extending to the upper right). In the ADP-Pi-bound state, the catalytic core binds weakly to actin. One head docks properly onto an actin binding site (green). The two myosin heads act independently, and only one attaches to actin at a time. Actin docking causes phosphate release from the active site. The lever arm then swings to the poststroke, ADP-bound state (red), which moves the actin filament by approximately 100 angstroms. After completing the stroke, ADP dissociates and ATP binds to the active site, which rapidly reverts the catalytic core to its weak-binding actin state. The lever arm will then recock back to its prestroke state (i.e., back to the start of the movie). The trailing head, which has released its phosphate (Pi) and detached its neck linker (red) from the core, is in the process of being thrown forward-
Descrição: dc.descriptionComponente Curricular::Educação Superior::Ciências Biológicas::Microbiologia-
Descrição: dc.descriptionComponente Curricular::Educação Superior::Ciências Exatas e da Terra::Química-
Idioma: dc.languageen-
Publicador: dc.publisherThe American Society for Cell Biology, ASBC Image & Video Library-
Relação: dc.relationA Moving Myosin Motor Protein.mov-
Direitos: dc.rightsYou may use the Images only for research and educational purposes in an educational institution. Images may be stored on a network server, hard drive or removable media, but only while this Agreement remains in effect. All of the Images you use must be accompanied by a notice stating, "© [Date and Author's or Owner's Name]. All rights reserved. Reprinted under license from The American Society for Cell Biology." The notice shall appear with the Images or on a credits page. "Educational purposes" means (i) non-commercial instruction or curriculum based teaching by educators to students at nonprofit educational institutions, (ii) planned non-commercial study, investigation or research directed toward making a contribution to a field of knowledge, or (iii) presentation of research findings at non-commercial peer conferences, workshops or seminars, but in any event there must be express written permission from ASCB before an Image can be published. "Educational institutions" include K-12 schools, colleges and universities. Libraries, museums, hospitals, research institutes and other nonprofit organizations are considered educational institutions when they engage in nonprofit instructional, research or scholarly activities for educational purposes-
???dc.source???: dc.sourcehttp://cellimages.ascb.org/cdm4/item_viewer.php?CISOROOT=/p4041coll12&CISOPTR=101&CISOBOX=1&REC=2-
Palavras-chave: dc.subjectEducação Superior::Ciências Biológicas::Microbiologia::Biologia e Fisiologia dos Microorganismos-
Palavras-chave: dc.subjectEducação Superior::Ciências Exatas e da Terra::Química::Estrutura, Conformação e Estereoquímica-
Palavras-chave: dc.subjectADP-
Palavras-chave: dc.subjectMyosin-
Palavras-chave: dc.subjectATP-
Palavras-chave: dc.subjectMuscle myosin-
Palavras-chave: dc.subjectMotor protein-
Título: dc.titleA moving myosin motor protein-
???dc.description2???: dc.description2To show the moving myosin motor protein-
???dc.description3???: dc.description3Duration: 29 min, 26 s. Original video created in November 2003. Original resource provided by Rosalind V Silverman-Gavrila. Work conducted at University of Toronto, Toronto, CA-
Aparece nas coleções:Repositório Institucional - MEC BIOE

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