Ring coupler moving via the 'forced walk' mechanism: a view of a single protofilament and its associated ring-subunit

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorEfremov, Artem-
Autor(es): dc.creatorGrishchuk, Ekaterina L.-
Autor(es): dc.creatorMcIntosh, J. Richard-
Autor(es): dc.creatorAtaullakhanov, Fazly I.-
Data de aceite: dc.date.accessioned2019-08-21T18:25:52Z-
Data de disponibilização: dc.date.available2019-08-21T18:25:52Z-
Data de envio: dc.date.issued2016-10-26-
Data de envio: dc.date.issued2016-10-26-
Fonte completa do material: dc.identifierhttp://acervodigital.unesp.br/handle/unesp/365507-
Fonte completa do material: dc.identifierhttp://objetoseducacionais2.mec.gov.br/handle/mec/22601-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/471713-
Descrição: dc.descriptionThis video shows configurations for a single protofilament and an associated ring subunit (Dam1 heterodecamer) for a ring-microtubule pair. Here, tubulin monomers are shown as green bars (separated with dots) that correspond to their vertical axes, so each linker ends approximately 2 nm away from the green line at the monomer's surface (shown as spheres on the first image only). The ring subunit and its linker move in 3D, but the movie shows only their 2D projection onto the plane of this protofilament. Each linker is predicted to walk in 8 nm steps along the same PF, just like a kinesin. In the current case, however, the energy for linker stepping comes from the protofilament bending to its equilibrium configuration. Although the individual linkers occasionally step backwards, the whole ring moves unidirectionally towards the MT minus end-
Descrição: dc.descriptionComponente Curricular::Educação Superior::Ciências Biológicas::Morfologia-
Publicador: dc.publisherThe American Society for Cell Biology, ASCB Image & Video Library-
Relação: dc.relationVideo 4. A View of.mov-
Direitos: dc.rightsYou may use the Images only for research and educational purposes in an educational institution. Images may be stored on a network server, hard drive or removable media, but only while this Agreement remains in effect. All of the Images you use must be accompanied by a notice stating, "© [Date and Author's or Owner's Name]. All rights reserved. Reprinted under license from The American Society for Cell Biology." The notice shall appear with the Images or on a credits page. "Educational purposes" means (i) non-commercial instruction or curriculum based teaching by educators to students at nonprofit educational institutions, (ii) planned non-commercial study, investigation or research directed toward making a contribution to a field of knowledge, or (iii) presentation of research findings at non-commercial peer conferences, workshops or seminars, but in any event there must be express written permission from ASCB before an Image can be published. "Educational institutions" include K-12 schools, colleges and universities. Libraries, museums, hospitals, research institutes and other nonprofit organizations are considered educational institutions when they engage in nonprofit instructional, research or scholarly activities for educational purposes-
Palavras-chave: dc.subjectCell-
Palavras-chave: dc.subjectProtofilament-
Palavras-chave: dc.subjectTubulin monomer-
Palavras-chave: dc.subjectEducação Superior::Ciências Biológicas::Morfologia::Citologia e Biologia Celular-
Título: dc.titleRing coupler moving via the 'forced walk' mechanism: a view of a single protofilament and its associated ring-subunit-
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