Comparative genomic analysis and mosquito larvicidal activity of four Bacillus thuringiensis serovar israelensis strains

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorAlves, Giselly B.-
Autor(es): dc.creatorMelo, Fernando L.-
Autor(es): dc.creatorOliveira, Eugenio E.-
Autor(es): dc.creatorHaddi, Khalid-
Autor(es): dc.creatorCosta, Lara T. M.-
Autor(es): dc.creatorDias, Marcelo L.-
Autor(es): dc.creatorCampos, Fabrício S.-
Autor(es): dc.creatorPereira, Eliseu J. G.-
Autor(es): dc.creatorCorrêa, Roberto F. T.-
Autor(es): dc.creatorAscêncio, Sergio D.-
Autor(es): dc.creatorSantos, Gil R.-
Autor(es): dc.creatorSmagghe, Guy-
Autor(es): dc.creatorRibeiro, Bergmann M.-
Autor(es): dc.creatorAguiar, Raimundo W. S.-
Data de aceite: dc.date.accessioned2026-02-09T12:54:52Z-
Data de disponibilização: dc.date.available2026-02-09T12:54:52Z-
Data de envio: dc.date.issued2020-08-31-
Data de envio: dc.date.issued2020-08-31-
Data de envio: dc.date.issued2019-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/42760-
Fonte completa do material: dc.identifierhttps://www.nature.com/articles/s41598-020-60670-7-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1170806-
Descrição: dc.descriptionBacillus thuringiensis serovar israelensis (Bti) is used to control insect vectors of human and animal diseases. In the present study, the toxicity of four strains of Bti, named T0124, T0131, T0137, and T0139, toward Aedes aegypti and Culex quinquefasciatus larvae was analyzed. The T0131 strain showed the highest larvicidal activity against A. aegypti (LC50 = 0.015 µg/ml) and C. quinquefasciatus larvae (LC50 = 0.035 µg/ml) when compared to the other strains. Furthermore, the genomic sequences of the four strains were obtained and compared. These Bti strains had chromosomes sizes of approximately 5.4 Mb with GC contents of ~35% and 5472–5477 putative coding regions. Three small plasmids (5.4, 6.8, and 7.6 kb) and three large plasmids (127, 235, and 359 kb) were found in the extrachromosomal content of all four strains. The SNP-based phylogeny revealed close relationship among isolates from this study and other Bti isolates, and SNPs analysis of the plasmids 127 kb did not reveal any mutations in δ-endotoxins genes. This newly acquired sequence data for these Bti strains may be useful in the search for novel insecticidal toxins to improve existing ones or develop new strategies for the biological control of important insect vectors of human and animal diseases.-
Idioma: dc.languageen-
Publicador: dc.publisherNature-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceScientific Reports-
Palavras-chave: dc.subjectInsect control-
Palavras-chave: dc.subjectLarvicidal activity-
Palavras-chave: dc.subjectInsects - Disease vector-
Palavras-chave: dc.subjectControle de insetos-
Palavras-chave: dc.subjectAtividade larvicida-
Palavras-chave: dc.subjectInsetos - Vetor de doenças-
Título: dc.titleComparative genomic analysis and mosquito larvicidal activity of four Bacillus thuringiensis serovar israelensis strains-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

Não existem arquivos associados a este item.