MERS coronavirus: an emerging zoonotic virus

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorLi, Fang-
Autor(es): dc.creatorDu, Lanying-
Data de aceite: dc.date.accessioned2026-02-09T12:54:39Z-
Data de disponibilização: dc.date.available2026-02-09T12:54:39Z-
Data de envio: dc.date.issued2020-03-25-
Data de envio: dc.date.issued2020-03-25-
Data de envio: dc.date.issued2019-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/39405-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1170728-
Descrição: dc.descriptionMiddle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus that was first reported in humans in June 2012 [1]. To date, MERS-CoV continues to infect humans with a fatality rate of ~35%. At least 27 countries have reported human infections with MERS-CoV (https://www.who.int/emergencies/mers-cov/en/). MERS-CoV is a zoonotic virus. Like severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV is believed to have originated from bats [2,3]. However, whereas the bat-to-human transmission of SARS-CoV was likely mediated by palm civets as intermediate hosts, humans likely acquired MERS-CoV from dromedary camels [4,5,6]. Human-to-human transmission of MERS-CoV does occur, but it is limited mostly to health care environments [7,8]. Moreover, whereas SARS-CoV recognizes angiotensin-converting enzyme 2 (ACE2) as a cellular receptor [9,10], MERS-CoV uses dipeptidyl peptidase 4 (DPP4) to enter target cells [11,12]. Currently, no vaccines or antiviral therapeutics have been approved for the prevention or treatment of MERS-CoV infection, although a number of them have been developed preclinically and/or tested clinically [13,14,15,16].-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherMDPI-
Direitos: dc.rightsAttribution 4.0 International-
Direitos: dc.rightsAttribution 4.0 International-
Direitos: dc.rightsacesso aberto-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
???dc.source???: dc.sourceViruses-
Palavras-chave: dc.subjectCoronavirus-
Palavras-chave: dc.subjectZoonotic virus-
Palavras-chave: dc.subjectSevere Acute Respiratory Syndrome (SARS)-
Palavras-chave: dc.subjectVírus zoonótico-
Palavras-chave: dc.subjectSíndrome respiratória aguda grave-
Título: dc.titleMERS coronavirus: an emerging zoonotic virus-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

Não existem arquivos associados a este item.