Toxicity of detoxified pie of ricinus communis in (Rattus Novergicus) wistar rats

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorMonteiro, Aline Gomes Dias Pinto-
Autor(es): dc.creatorCosta, Rafael Carneiro-
Autor(es): dc.creatorVaraschin, Mary Suzan-
Autor(es): dc.creatorSousa, Raimundo Vicente de-
Autor(es): dc.creatorGuerreiro, Mário César-
Data de aceite: dc.date.accessioned2026-02-09T12:50:08Z-
Data de disponibilização: dc.date.available2026-02-09T12:50:08Z-
Data de envio: dc.date.issued2019-02-15-
Data de envio: dc.date.issued2023-06-27-
Data de envio: dc.date.issued2019-02-15-
Data de envio: dc.date.issued2023-06-27-
Data de envio: dc.date.issued2016-06-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br//handle/1/57294-
Fonte completa do material: dc.identifierhttps://www.academiapublishing.org/journals/ajpp/abstract/2016/Apr%20-%20Jun/Monteiro%20et%20al.htm-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1169189-
Descrição: dc.descriptionProcessing castor seed produces castor oil as the main product and castor pie crust and bran as the co-products. In this work, the castor pie was studied and treated, both as a raw material and the noble, which is widely used for fertilization due to significant amounts of nitrogen. However, because this material is also composed of a significant amount of protein, it could also be used as feed for ruminants. Unfortunately, due to the presence of the highly toxic component ricin, its use in feed is impeded. This study aims to demonstrate the efficiency of oxy-detoxification, using Fenton-type systems developed for castor bean, by in vivo testing so that the pie could be used as a protein supplement in animal feed and therefore add value to the supply chain of the oilseed. The detoxified castor bean meal used in this study was treated by oxidative reactions using a homogeneous catalytic system of Fe(III) and H2O2. The efficiency of the procedure was verified through weight gain and growth of the animals, histopathological analysis of the different organs and hematological values. The development of the animals was not harmed by the levels of detoxified pie added to their diets as compared with growth in control animals (fed with standard diets). At the end of the experiment, the animals were euthanized and their analyzed tissues showed no microscopic lesions. The results showed that it is possible to preserve the nutritional properties of lignocellulosic material by removing the non-toxic levels of ricin and trypsin inhibitors from the pie by treatment using Fenton-type systems.-
Idioma: dc.languageen-
Publicador: dc.publisherAcademia Publishing-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceJournal of Pharmacy and Pharmacology-
Palavras-chave: dc.subjectCastor bean-
Palavras-chave: dc.subjectOxy-detoxification-
Palavras-chave: dc.subjectToxicity and food supplement-
Palavras-chave: dc.subjectOxi-desintoxicação-
Palavras-chave: dc.subjectToxicidade e suplemento alimentar-
Título: dc.titleToxicity of detoxified pie of ricinus communis in (Rattus Novergicus) wistar rats-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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