Morphological analysis of colon goblet cells and submucosa in type I diabetic rats submitted to physical training

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorRemedio, Rafael Neodini-
Autor(es): dc.creatorCastellar, Alexandre-
Autor(es): dc.creatorBarbosa, Rodrigo Avelaira-
Autor(es): dc.creatorGomes, Ricardo José-
Autor(es): dc.creatorCaetano, Flávio Henrique-
Data de aceite: dc.date.accessioned2026-02-09T12:36:10Z-
Data de disponibilização: dc.date.available2026-02-09T12:36:10Z-
Data de envio: dc.date.issued2020-07-15-
Data de envio: dc.date.issued2020-07-15-
Data de envio: dc.date.issued2011-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/41960-
Fonte completa do material: dc.identifierhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jemt.22000-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1164593-
Descrição: dc.descriptionColon layers, especially the submucosa, as well as the secretion of goblet cells are extremely important for the functioning and transit of substances in this organ. However, the damages arising from type I diabetes and the effects of physical training, which plays crucial role in the treatment of this disease, are not yet known in these regions. To analyze the changes in colon submucosa and goblet cells of diabetic rats, as well as the effects of physical training, Wistar rats were divided into four groups: sedentary control, trained control, sedentary diabetic (SD), and trained diabetic (TD). The training protocol consisted of swimming for 60 min a day, 5 days per week, during 8 weeks. Colon samples were collected, processed, and evaluated by histochemical and ultrastructural techniques. Goblet and submucosa cells did not show alterations in shape, size, protein and carbohydrate content, in all treatment groups. Decreased amount of collagen fibers, however, was observed in the submucosa and lamina propria of SD rats, but this alteration was recovered in TDs. The ultrastructural analysis, in turn, revealed greater quantity of Golgi apparatus cisterns in SDs, distinctly than TDs, which showed improvement in this diabetic condition. Thus, physical training was responsible for the recovery of some important diabetic alterations, possibly improving the motility of substances in the large intestine. Nevertheless, it cannot be considered alone in the treatment of this disease, requiring the combined practice of other methods. Microsc. Res. Tech. 75:821–828, 2012. © 2011 Wiley Periodicals, Inc.-
Idioma: dc.languageen-
Publicador: dc.publisherWiley-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceMicroscopy Research & Technique-
Palavras-chave: dc.subjectColon goblet cells-
Palavras-chave: dc.subjectSedentary diabetic-
Palavras-chave: dc.subjectTrained diabetic-
Palavras-chave: dc.subjectLarge intestine-
Palavras-chave: dc.subjectCélula caliciforme-
Palavras-chave: dc.subjectDiabético sedentário-
Palavras-chave: dc.subjectDiabéticos treinados-
Palavras-chave: dc.subjectIntestino grosso-
Título: dc.titleMorphological analysis of colon goblet cells and submucosa in type I diabetic rats submitted to physical training-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

Não existem arquivos associados a este item.