B-cell engineering: a promising approach towards vaccine development for COVID-19

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorFaiq, Muneeb A.-
Data de aceite: dc.date.accessioned2026-02-09T12:32:50Z-
Data de disponibilização: dc.date.available2026-02-09T12:32:50Z-
Data de envio: dc.date.issued2020-06-16-
Data de envio: dc.date.issued2020-06-16-
Data de envio: dc.date.issued2020-10-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/41456-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S030698772030791X-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1163479-
Descrição: dc.descriptionWith the number of cases crossing six million (and more than three hundred and seventy thousand deaths) worldwide, there is a dire need of a vaccine (and repurposing of drugs) for SARS-CoV-2 disease (COVID-19). It can be argued that a vaccine may be the most efficient way to contain the spread of this disease and prevent its future onset. While many attempts are being made to design and develop a vaccine for SARS-CoV-2, pertinent technological hitches do exist. That is perhaps one of the reasons that we don’t have vaccine for coronaviruses (including SARS-CoV-1 and MERS). Recently developed CRISPR-mediated genome editing approach can be repurposed into a cell-modification endeavor in addition to (and rather than) correcting defective parts of genome. With this premise, B-cells can be engineered into universal donor, antigen specific, perpetually viable, long lasting, non-oncogenic, relatively benign, antibody producing cells which may serve as an effective vaccine for SARS-CoV-2 and, by the same rationale, other viruses and pathogens.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceMedical Hypotheses-
Palavras-chave: dc.subjectVaccine-
Palavras-chave: dc.subjectGenome editing-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectCoronavirus-
Palavras-chave: dc.subjectB-cell-
Palavras-chave: dc.subjectAntibody-
Título: dc.titleB-cell engineering: a promising approach towards vaccine development for COVID-19-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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