Mitochondrial-targeted ubiquinone: a potential treatment for COVID-19

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorOuyang, Lichen-
Autor(es): dc.creatorGong, Jie-
Data de aceite: dc.date.accessioned2026-02-09T12:23:07Z-
Data de disponibilização: dc.date.available2026-02-09T12:23:07Z-
Data de envio: dc.date.issued2020-09-11-
Data de envio: dc.date.issued2020-09-11-
Data de envio: dc.date.issued2020-10-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/42995-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0306987720314262-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1160216-
Descrição: dc.descriptionImmune dysregulation characterized by T cell exhaustion and high level of inflammatory cytokines is associated with severe COVID-19. Figuring out the early event of immune dysregulation would provide a potential treatment for COVID-19. Recent evidence indicate that mitochondrial dysfunction participates in the development of COVID-19 and may be responsible for the dysregulated immune response. Mitochondrial-targeted ubiquinone (MitoQ), a mitochondrial-targeted antioxidant, shows beneficial effects on various diseases through improving mitochondrial dysfunction. We hypothesize that MitoQ could act as a potential treatment in COVID-19. MitoQ may alleviate cytokine storm and restore the function of exhausted T cells in COVID-19 patients through improving mitochondrial dysfunction. In this article, we provide evidence to support the use of MitoQ as a potential treatment or adjunct therapy in the context of COVID-19.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceMedical Hypotheses-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectT cell exhaustion-
Palavras-chave: dc.subjectMitochondrial dysfunction-
Palavras-chave: dc.subjectMitochondrial-targeted ubiquinone (MitoQ)-
Palavras-chave: dc.subjectSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-
Título: dc.titleMitochondrial-targeted ubiquinone: a potential treatment for COVID-19-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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