In vitro antimicrobial activity of solution blow spun poly(lactic acid)/polyvinylpyrrolidone nanofibers loaded with Copaiba (Copaifera sp.) oil

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorBonan, Roberta F.-
Autor(es): dc.creatorBonan, Paulo R. F.-
Autor(es): dc.creatorBatista, André U. D.-
Autor(es): dc.creatorSampaio, Fábio C.-
Autor(es): dc.creatorAlbuquerque, Allan J. R.-
Autor(es): dc.creatorMoraes, Maria C. B.-
Autor(es): dc.creatorMattoso, Luiz H. C.-
Autor(es): dc.creatorGlenn, Gregory M.-
Autor(es): dc.creatorMedeiros, Eliton S.-
Autor(es): dc.creatorOliveira, Juliano E.-
Data de aceite: dc.date.accessioned2026-02-09T12:20:03Z-
Data de disponibilização: dc.date.available2026-02-09T12:20:03Z-
Data de envio: dc.date.issued2020-01-28-
Data de envio: dc.date.issued2020-01-28-
Data de envio: dc.date.issued2015-03-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/38754-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0928493114008194#!-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1159197-
Descrição: dc.descriptionIn this study poly(lactic acid) (PLA) and polyvinylpyrrolidone (PVP) micro- and nanofiber mats loaded with Copaiba (Copaifera sp.) oil were produced by solution blow spinning (SBS). The Copaiba (Copaifera sp.) oil was characterized by gas chromatography (GC). Neat PLA and four PLA/PVP blends containing 20% (wt.%) oil were spun and characterized by scanning electron microscopy (SEM) and by studying the surface contact angle, in vitro release rate, and antimicrobial activity. All compositions evaluated were able to produce continuous and smooth fibers by SBS. The addition of PVP increased fiber diameter, and decreased the surface contact angle. GC analysis demonstrated that the main component of the Copaiba oil was β-caryophyllene, a known antimicrobial agent. In vitro release tests of Copaiba oil volatiles demonstrated a higher release rate in fibers containing PVP. Fiber mats made from blends containing higher amounts of PVP had greater antimicrobial action against Staphylococcus aureus. The results confirm the potential of the fiber mats for use in controlled drug release and could lead to promising applications in the biomedical field.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceMaterials Science and Engineering: C-
Palavras-chave: dc.subjectNanofibers-
Palavras-chave: dc.subjectDrug delivery system-
Palavras-chave: dc.subject(Copaifera sp.) oil-
Palavras-chave: dc.subjectSolution blow spinning-
Palavras-chave: dc.subjectAntimicrobial activity-
Palavras-chave: dc.subjectCopaiba oil-
Título: dc.titleIn vitro antimicrobial activity of solution blow spun poly(lactic acid)/polyvinylpyrrolidone nanofibers loaded with Copaiba (Copaifera sp.) oil-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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