Phenolic profiling and in vitro bioactivity of Moringa oleifera leaves as affected by different extraction solvents

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorRocchetti, Gabriele-
Autor(es): dc.creatorPagnossa, Jorge Pamplona-
Autor(es): dc.creatorBlasi, Francesca-
Autor(es): dc.creatorCossignani, Lina-
Autor(es): dc.creatorPiccoli, Roberta Hilsdorf-
Autor(es): dc.creatorZengin, Gokhan-
Autor(es): dc.creatorMontesano, Domenico-
Autor(es): dc.creatorCocconcelli, Pier Sandro-
Autor(es): dc.creatorLucini, Luigi-
Data de aceite: dc.date.accessioned2026-02-09T12:13:57Z-
Data de disponibilização: dc.date.available2026-02-09T12:13:57Z-
Data de envio: dc.date.issued2020-06-15-
Data de envio: dc.date.issued2020-06-15-
Data de envio: dc.date.issued2019-12-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/41433-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0963996919305988#!-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1157135-
Descrição: dc.descriptionIn this work the (poly)-phenolic profile of Moringa oleifera leaves was comprehensively investigated through untargeted metabolomics, following a homogenizer-assisted extraction (HAE) using three solvent systems, i.e. methanol (HAE-1), methanol-water 50:50 v/v (HAE-2) and ethyl acetate (HAE-3). This approach allowed to putatively annotate 291 compounds, recording mainly flavonoids and phenolic acids. Thereafter, antioxidant capacity, antimicrobial activity and enzyme inhibition were assayed in the different extracts. HAE-1 extract showed the highest total phenolic content (31.84 mg/g), followed by HAE-2 (26.95 mg/g) and HAE-3 (14.71 mg/g). In addition, HAE-1 and HAE-2 extracts exhibited an expressive activity against Bacillus cereus and Listeria innocua. The HAE-2 leaf extract was characterized by the highest DPPH and ABTS values (being 49.55 and 45.26 mgTE/g), while ferric reducing antioxidant power was found to be higher in HAE-1 (58.26 mgTE/g). Finally, the enzyme inhibitory effects of M. oleifera leaf extracts were investigated against five enzymes, namely acetylcholinesterase (AChE), butyrylcholinesterase (BChE), tyrosinase, α-amylase and α-glucosidase. All of the tested extracts exhibited inhibitory effects on AChE and BChE with a higher activity for HAE-3 and HAE-1, whilst HAE-1 showed the higher impact on tyrosinase, glucosidase and amylase activities. Taken together, these findings suggest that M. oleifera leaf extracts are a good source of bioactive polyphenols with a potential use in food and pharma industries.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceFood Research International-
Palavras-chave: dc.subjectMoringa-
Palavras-chave: dc.subjectFood metabolomics-
Palavras-chave: dc.subjectEnzymatic activity-
Palavras-chave: dc.subjectAntioxidant activity-
Palavras-chave: dc.subjectAntimicrobial activity-
Palavras-chave: dc.subjectAcácia-branca-
Palavras-chave: dc.subjectMetabolômica alimentar-
Palavras-chave: dc.subjectAtividade enzimática-
Palavras-chave: dc.subjectAtividade antioxidante-
Palavras-chave: dc.subjectAtividade antimicrobiana-
Título: dc.titlePhenolic profiling and in vitro bioactivity of Moringa oleifera leaves as affected by different extraction solvents-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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