Protective immunity after COVID-19 has been questioned: what can we do without SARS-CoV-2-IgG detection?

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorMelgaço, Juliana Gil-
Autor(es): dc.creatorAzamor, Tamiris-
Autor(es): dc.creatorAno Bom, Ana Paula Dinis-
Data de aceite: dc.date.accessioned2026-02-09T12:12:40Z-
Data de disponibilização: dc.date.available2026-02-09T12:12:40Z-
Data de envio: dc.date.issued2020-05-14-
Data de envio: dc.date.issued2020-05-14-
Data de envio: dc.date.issued2020-04-28-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/40911-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0008874920302501-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1156677-
Descrição: dc.descriptionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a severe acute respiratory syndrome that is called COVID-19. Clinical manifestations of COVID-19 include diarrhea, pneumonia, lymphopenia, exhausted lymphocytes, and pro-inflammatory cytokine production. Immunology is part of the process of clinical evolution, but there are some questions around immunity-based protection: (1) why some infected people have only mild symptoms of the disease or are asymptomatic; (2) why delayed and weak antibody responses are associated with severe outcomes; and (3) why positivity in molecular tests does not represent protective antibody IgG. Perhaps T cell responses may be the key to solving those questions. SARS-CoV-2-specific memory T cells persist in peripheral blood and may be capable of providing effective information about protective immunity. The T cells studies can be helpful in elucidating the pathways for development of vaccines, therapies, and diagnostics for COVID-19 and for filling these immunology knowledge gaps.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceCellular Immunology-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectCoronavirus-
Palavras-chave: dc.subjectSARS-CoV-2-
Título: dc.titleProtective immunity after COVID-19 has been questioned: what can we do without SARS-CoV-2-IgG detection?-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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