Use of hydroxychloroquine and interferon alpha-2b for the prophylaxis of COVID-19

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorYang, Alexander-
Autor(es): dc.creatorYang, Charlotte-
Autor(es): dc.creatorYang, Bing-
Data de aceite: dc.date.accessioned2026-02-09T12:06:25Z-
Data de disponibilização: dc.date.available2026-02-09T12:06:25Z-
Data de envio: dc.date.issued2020-06-22-
Data de envio: dc.date.issued2020-06-22-
Data de envio: dc.date.issued2020-10-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/41525-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S030698772030709X-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1154440-
Descrição: dc.descriptionThe ongoing pandemic of COVID-19 infection demands efforts to reduce spread. In order to eradicate an infectious disease, a method of prevention with low social cost is the most effective way. While we wait for new therapies and a vaccine, we are proposing a solution based on the existing knowledge in biomedical sciences. Here we propose to use low doses of hydroxychloroquine (50–100 mg daily orally) and intranasal interferon alpha-2b (IFN α-2b) spray (0.5 × 106 IU twice daily) for the prophylaxis of COVID-19. Although there are ongoing clinical trials to test the efficacy of hydroxychloroquine for prophylaxis, there has not been any proposal to test the efficacy of IFN α-2b together with hydroxychloroquine to increase protection against COVID-19. Since the two act on two different mechanisms, we strongly believe that the two could have additive effects in prophylaxis against COVID-19. We recommend using a randomized control study to prove efficacy and safety.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceMedical Hypotheses-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectHydroxychloroquine-
Palavras-chave: dc.subjectInterferon alpha-2b-
Título: dc.titleUse of hydroxychloroquine and interferon alpha-2b for the prophylaxis of COVID-19-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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