Beneficial effects of flaxseed and/or mulberry extracts supplementation in ovariectomized wistar rats

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorPereira, Jéssica Petrine Castro-
Autor(es): dc.creatorOliveira, Erika Aparecida-
Autor(es): dc.creatorPereira, Fernanda Aparecida Castro-
Autor(es): dc.creatorSeixas, Josilene Nascimento-
Autor(es): dc.creatorGuimaraes, Camila Souza de Oliveira-
Autor(es): dc.creatorBorges, Bruno Del Bianco-
Data de aceite: dc.date.accessioned2026-02-09T12:05:59Z-
Data de disponibilização: dc.date.available2026-02-09T12:05:59Z-
Data de envio: dc.date.issued2022-09-27-
Data de envio: dc.date.issued2022-09-27-
Data de envio: dc.date.issued2022-08-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/55212-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1154288-
Descrição: dc.descriptionLow endogenous estrogen action causes several injuries. Medicinal plants, such as flaxseed and mulberry, contain substances that have been shown to be effective to the organism. The aim was to verify the effects of flaxseed and/or mulberry extracts on ovariectomized Wistar rats. The animals received supplements of extracts and estrogen or saline by gavage for 60 days and were weighed weekly. Vaginal wash, blood, pituitary, uterus, liver, and kidneys were collected. Phenolic compounds and the antioxidant activity of the extracts, lipid profile, uric acid, liver enzymes, and pituitary weight were measured. Histomorphometric for uterine wall and histopathological analyses for liver and kidney were performed. Flaxseed and mulberry extracts showed great antioxidant activity and large amounts of phenolic compounds. The treatment with extracts had less weight gain, increased pituitary weight, the predominance of vaginal epithelial cells, and reduced TC, LDL-c and lipase activity, similar to estrogen animals. Estrogen or flaxseed + mulberry animals reduced VLDL-c and TAG. HDL-c, uric acid, and liver enzymes did not differ. Estrogen or extracts demonstrated trophic action on the endometrial thickness and have not shown hepatotoxicity or nephrotoxicity. We suggested the beneficial effects of flaxseed and mulberry extract as an alternative to reduce and/or prevent the negative effects caused by low estrogenic action.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)-
Direitos: dc.rightsAttribution 4.0 International-
Direitos: dc.rightsAttribution 4.0 International-
Direitos: dc.rightsacesso aberto-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
???dc.source???: dc.sourceNutrients-
Palavras-chave: dc.subjectPhytoestrogens-
Palavras-chave: dc.subjectAntioxidants-
Palavras-chave: dc.subjectEstrogen-
Palavras-chave: dc.subjectCompound phenolics-
Palavras-chave: dc.subjectMetabolism-
Palavras-chave: dc.subjectBody weight-
Palavras-chave: dc.subjectFitoestrógenos-
Palavras-chave: dc.subjectAntioxidantes-
Palavras-chave: dc.subjectEstrogênio-
Palavras-chave: dc.subjectCompostos fenólicos-
Palavras-chave: dc.subjectMetabolismo-
Palavras-chave: dc.subjectPeso corporal-
Palavras-chave: dc.subjectRatas - Ovariectomia-
Título: dc.titleBeneficial effects of flaxseed and/or mulberry extracts supplementation in ovariectomized wistar rats-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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