COVID-19, SARS and MERS: are they closely related?

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorPetrosillo, Nicola-
Autor(es): dc.creatorViceconte, Giulio-
Autor(es): dc.creatorErgonul, Onder-
Autor(es): dc.creatorIppolito, Giuseppe-
Autor(es): dc.creatorPetersen, Eskild-
Data de aceite: dc.date.accessioned2026-02-09T12:03:24Z-
Data de disponibilização: dc.date.available2026-02-09T12:03:24Z-
Data de envio: dc.date.issued2020-03-31-
Data de envio: dc.date.issued2020-03-31-
Data de envio: dc.date.issued2020-03-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/39611-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S1198743X20301713-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1153368-
Descrição: dc.descriptionBackground The 2019 novel coronavirus (SARS-CoV-2) is a new human coronavirus which is spreading with epidemic features in China and other Asian countries with cases reported worldwide. This novel Coronavirus Disease (COVID-19) is associated with a respiratory illness that may cause severe pneumonia and acute respiratory distress syndrome (ARDS). Although related to the Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS), COVID-19 shows some peculiar pathogenetic, epidemiological and clinical features which have not been completely understood to date. Objectives We provide a review of the differences in terms of pathogenesis, epidemiology and clinical features between COVID-19, SARS and MERS. Sources The most recent literature in English language regarding COVID-19 has been reviewed and extracted data have been compared with the current scientific evidence about SARS and MERS epidemics. Content COVID-19 seems not to be very different from SARS regarding its clinical features. However, it has a fatality rate of 2.3%, lower than SARS (9.5%) and much lower than MERS (34.4%). It cannot be excluded that because of the COVID-19 less severe clinical picture it can spread in the community more easily than MERS and SARS. The actual basic reproductive number (R0) of COVID-19 (2-2.5) is still controversial. It is probably slightly higher than the R0 of SARS (1.7-1.9) and higher than MERS (<1),. The gastrointestinal route of transmission of SARS-CoV-2, which has been also assumed for SARS-CoV and MERS-CoV, cannot be ruled out and needs to be further investigated. Implications There is still much more to know about COVID-19, especially as concerns mortality and capacity of spreading on a pandemic level. Nonetheless, all of the lessons we learned in the past from SARS and MERS epidemics are the best cultural weapons to face this new global threat.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceClinical Microbiology and Infection-
Palavras-chave: dc.subjectCoronavirus-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectEmerging infections-
Palavras-chave: dc.subjectMiddle East Respiratory Syndrome (MERS)-
Palavras-chave: dc.subjectSevere Acute Respiratory Syndrome (SARS)-
Título: dc.titleCOVID-19, SARS and MERS: are they closely related?-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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