(R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorPacule, Horácio B.-
Autor(es): dc.creatorVanegas, Javier A. G.-
Autor(es): dc.creatorTerra, Willian C.-
Autor(es): dc.creatorCampos, Vicente P.-
Autor(es): dc.creatorOliveira, Denilson F.-
Data de aceite: dc.date.accessioned2026-02-09T12:03:21Z-
Data de disponibilização: dc.date.available2026-02-09T12:03:21Z-
Data de envio: dc.date.issued2022-10-26-
Data de envio: dc.date.issued2022-10-26-
Data de envio: dc.date.issued2022-10-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/55355-
Fonte completa do material: dc.identifierhttps://doi.org/10.1016/j.exppara.2022.108359-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1153349-
Descrição: dc.descriptionTo contribute to the development of new fumigant nematicides for the control of the plant-parasitic nematode Meloidogyne incognita, this study started with 31 volatile organic compounds reported as toxic to nematodes. At 500 μg/mL, α-ionone, (S)-carvone, (R)-carvone, 2-methylpropyl acetate, undecan-2-one, decan-2-one, and dodecan-2-one caused mortalities to M. incognita second-stage juveniles (J2) that were similar to those obtained with the commercial nematicides carbofuran (170 μg/mL) and fluensulfone (42.2 μg/mL). (R)-carvone, with a lethal concentration to 50% J2 (LC50) equal to 524 μg/mL, was selected for subsequent studies. When J2 were exposed to the (R)-carvone solution, the infectivity and reproduction on tomato were reduced. In the M. incognita egg hatching assay, (R)-carvone behaved like a true ovicide. When employed as a fumigant, (R)-carvone (3.9 g/L) was as efficient as the soil fumigant dazomet (0.245 g/L) in eliminating eggs of the nematode in a substrate to be used for tomato planting. According to in silico studies employing pharmacophoric searches and molecular docking, acetylcholinesterases are the target of (R)-carvone in the nematode.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceExperimental Parasitology-
Palavras-chave: dc.subjectRoot-knot nematode-
Palavras-chave: dc.subjectComputational chemistry-
Palavras-chave: dc.subjectVolatile organic compounds-
Palavras-chave: dc.subjectMolecular docking-
Palavras-chave: dc.subjectTomato-
Palavras-chave: dc.subjectNematoides-das-galhas-
Palavras-chave: dc.subjectQuímica computacional-
Palavras-chave: dc.subjectCompostos orgânicos voláteis-
Palavras-chave: dc.subjectAncoragem molecular-
Palavras-chave: dc.subjectTomate-
Título: dc.title(R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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