Selective activity of Mucor plumbeus reductase towards (−)-camphorquinone

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorSouza, Giovanni Gontijo de-
Autor(es): dc.creatorAnconi, Cleber Paulo Andrada-
Autor(es): dc.creatorCornelissen, Sjef-
Autor(es): dc.creatorAlmeida, Wagner Batista de-
Autor(es): dc.creatorSantos, Hélio Ferreira dos-
Autor(es): dc.creatorFortes, Isabel Cristina Pereira-
Autor(es): dc.creatorTakahashi, Jacqueline Aparecida-
Data de aceite: dc.date.accessioned2026-02-09T11:49:30Z-
Data de disponibilização: dc.date.available2026-02-09T11:49:30Z-
Data de envio: dc.date.issued2017-07-13-
Data de envio: dc.date.issued2017-07-13-
Data de envio: dc.date.issued2009-08-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/13325-
Fonte completa do material: dc.identifierhttps://link.springer.com/article/10.1007%2Fs10295-009-0583-2-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1148264-
Descrição: dc.descriptionThe biotransformation of 1R-(-)-camphorquinone, achieved by growing cells of four fungi species isolated from soil (Mucor plumbeus, Lecanicillium muscarium, Thamnostylum sp. and Syncephalastrum racemosum), was investigated in optimized culture media for each species. Fungi were grown aerobically under shaking and their activities with respect to camphorquinone were monitored for 20 days by gas chromatography coupled to mass spectrometry (GCMS). Camphorquinone was found to be stable in control flasks throughout the experiment. The most interesting results were found for M. plumbeus, which was only able to perform monoreduction of camphorquinone when cultivated on a glucose-peptone-yeast extract medium. Large-scale experiments were set up and the camphorquinone biotransformation products formed by M. plumbeus were purified by column chromatography and identified by (1)H and (13)C nuclear magnetic resonance (NMR). Theoretical calculations were employed as a complementary technique to unambiguously identify the biotransformation products. These findings suggest that M. plumbeus could be of great use for the selective reduction of camphorquinone and related compounds.-
Idioma: dc.languageen-
Publicador: dc.publisherSpringer-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceJournal of Industrial Microbiology & Biotechnology-
Palavras-chave: dc.subjectCamphorquinone-
Palavras-chave: dc.subjectBiotransformation-
Palavras-chave: dc.subjectMucor plumbeus-
Palavras-chave: dc.subjectStereoselectivity-
Palavras-chave: dc.subjectBiotransformação-
Palavras-chave: dc.subjectEstereosselectividade-
Título: dc.titleSelective activity of Mucor plumbeus reductase towards (−)-camphorquinone-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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