Pathologic, histochemical, and immunohistochemical findings in pulmonary and encephalitic cryptococcosis in a goat

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Autor(es): dc.creatorHeadley, Selwyn A.-
Autor(es): dc.creatorPimentel, Luciano A.-
Autor(es): dc.creatorMichelazzo, Mariana Z.-
Autor(es): dc.creatorToma, Hugo S.-
Autor(es): dc.creatorPretto-Giordano, Lucienne G.-
Autor(es): dc.creatorMarcasso, Rogério A.-
Autor(es): dc.creatorAmude, Alexandre M.-
Autor(es): dc.creatorOliveira, Thalita E.-
Autor(es): dc.creatorSantos, Marcelo D.-
Autor(es): dc.creatorKrockenberger, Mark-
Data de aceite: dc.date.accessioned2026-02-09T11:48:10Z-
Data de disponibilização: dc.date.available2026-02-09T11:48:10Z-
Data de envio: dc.date.issued2019-04-23-
Data de envio: dc.date.issued2023-06-27-
Data de envio: dc.date.issued2019-04-23-
Data de envio: dc.date.issued2023-06-27-
Data de envio: dc.date.issued2019-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br//handle/1/57330-
Fonte completa do material: dc.identifierhttps://journals.sagepub.com/doi/full/10.1177/1040638718816358-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1147788-
Descrição: dc.descriptionWe describe the pathologic, histochemical, and immunohistochemical findings associated with pulmonary and encephalitic cryptococcosis in a 3-y-old, mixed-breed, nanny goat from central-west Brazil. The goat had progressive neurologic signs over 30 d; cryptococcosis was diagnosed antemortem by cytologic evaluation of cerebrospinal fluid. Treatment was initiated, but the animal died spontaneously shortly thereafter. Grossly, there was a large space-occupying gelatinous mass (cryptococcoma) in the left lung and smaller masses in the cerebral temporal and frontal cortex, thalamus, hippocampus, basal nuclei, and mesencephalon with consequent internal hydrocephalus. Histologic evaluation revealed marked granulomatous cryptococcal pneumonia and meningoencephalitis. Intralesional narrow-necked budding cryptococcal yeasts were identified on special stains (Mayer mucicarmine and Grocott methenamine silver) in sections of lung and brain. Immunohistochemistry utilizing a panel of monoclonal antibodies that selectively label capsules of Cryptococcus spp. was consistent with C. neoformans var. grubii.-
Idioma: dc.languageen-
Publicador: dc.publisherSAGE Journals-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceJournal of Veterinary Diagnostic Investigation-
Palavras-chave: dc.subjectCryptococcal leptomeningitis-
Palavras-chave: dc.subjectCryptococcoma-
Palavras-chave: dc.subjectDiagnostic pathology-
Palavras-chave: dc.subjectPatologia diagnóstica-
Palavras-chave: dc.subjectCriptococose pulmonar-
Título: dc.titlePathologic, histochemical, and immunohistochemical findings in pulmonary and encephalitic cryptococcosis in a goat-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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