The liver injury and gastrointestinal symptoms in patients with Coronavirus Disease 19: a systematic review and meta-analysis

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorWang, Haizhou-
Autor(es): dc.creatorQiu, Peishan-
Autor(es): dc.creatorLiu, Jing-
Autor(es): dc.creatorWang, Fan-
Autor(es): dc.creatorZhao, Qiu-
Data de aceite: dc.date.accessioned2026-02-09T11:38:20Z-
Data de disponibilização: dc.date.available2026-02-09T11:38:20Z-
Data de envio: dc.date.issued2020-05-27-
Data de envio: dc.date.issued2020-05-27-
Data de envio: dc.date.issued2019-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/41252-
Fonte completa do material: dc.identifierhttp://www.sciencedirect.com/science/article/pii/S2210740120301170-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1144103-
Descrição: dc.descriptionBackgrounds Since December 2019, novel coronavirus (SARS-CoV-2)-infected pneumonia (COVID-19) occurred in Wuhan, and rapidly spread throughout China. Our study aimed to evaluate the association of liver injury and gastrointestinal symptoms (GIS) with the progression of COVID-19. Methods A comprehensive search was performed on the PubMed to identify eligible studies that summarized the liver injury and GIS in COVID-19. Results A total of 21 studies with 3024 patients were included. Up to 53% patients had liver dysfunctions and the degree of liver damage was associated the severity of the disease. The prevalence of diarrhoea, nausea/vomiting or abdominal pain in patients with COVID-19 were 9.1%, 5.2% and 3.5%, respectively. No significant was found in the prevalence of diarrhoea (OR, 1.24; 95%CI, 0.90 to 1.72; I2 = 0%, P = 0.19) and nausea/vomiting (OR, 1.24; 95%CI, 0.57 to 2.69; I2 = 61%, P = 0.58) between severe and non-severe patients. In addition, diarrhoea (OR, 1.22; 95%CI, 0.50 to 2.98; I2 = 0%, P = 0.66) and nausea/vomiting (OR, 1.09; 95%CI, 0.46 to 2.62; I2 = 0%, P = 0.84) were not associated with the prognosis of COVID-19 patients. Conclusions The incidences of GIS in patients with COVID-19 is relatively low and are not associated with the COVID-19 progression. Gastroenterologists should pay more attention to the liver injury induced by SARS-CoV-2 during the course of infection.-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceClinics and Research in Hepatology and Gastroenterology-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-
Palavras-chave: dc.subjectLiver injury-
Palavras-chave: dc.subjectDiarrhoea-
Palavras-chave: dc.subjectGastrointestinal symptoms-
Título: dc.titleThe liver injury and gastrointestinal symptoms in patients with Coronavirus Disease 19: a systematic review and meta-analysis-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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