Current approaches against Alzheimer's disease in clinical trials

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorKuca, Kamil-
Autor(es): dc.creatorSoukup, Ondrej-
Autor(es): dc.creatorMaresova, Petra-
Autor(es): dc.creatorKorabecny, Jan-
Autor(es): dc.creatorNepovimova, Eugenie-
Autor(es): dc.creatorKlimova, Blanka-
Autor(es): dc.creatorHonegr, Jan-
Autor(es): dc.creatorRamalho, Teodorico C.-
Autor(es): dc.creatorFrança, Tanos C. C.-
Data de aceite: dc.date.accessioned2026-02-09T11:35:36Z-
Data de disponibilização: dc.date.available2026-02-09T11:35:36Z-
Data de envio: dc.date.issued2019-09-06-
Data de envio: dc.date.issued2019-09-06-
Data de envio: dc.date.issued2016-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/36716-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1143093-
Descrição: dc.descriptionAlzheimer's disease (AD) is a progressive degenerative brain disease which causes mental and physical decline, gradually resulting in death. Currently, this disease represents one of the uppermost human issues, both from the medical and economic point of view. Interest in the discovery of a drug for AD is enormous. However, despite the long-term and worldwide effort for a more effective therapy, the only available treatment is a symptomatic use of acetylcholinesterase inhibitors (AChEIs) and memantine. New therapeutic approaches as well as those based on cholinergic or amyloid theory have not brought the desired benefits yet. Thus, the question is whether an effective drug for this progressive disease will ever be developed or whether people will have to rely only on prevention and minimize risk factors of AD.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherSociedade Brasileira de Química-
Direitos: dc.rightsacesso aberto-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
???dc.source???: dc.sourceJournal of the Brazilian Chemical Society-
Palavras-chave: dc.subjectAlzheimer's disease - Treatment-
Palavras-chave: dc.subjectAcetylcholinesterase inhibitors-
Palavras-chave: dc.subjectDoença de Alzheimer - Tratamento-
Palavras-chave: dc.subjectInibidores da acetilcolinesterase-
Título: dc.titleCurrent approaches against Alzheimer's disease in clinical trials-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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