Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorSimão, Anderson Assaid-
Autor(es): dc.creatorMarques, Tamara R.-
Autor(es): dc.creatorMarcussi, Silvana-
Autor(es): dc.creatorCorrea, Angelita Duarte-
Data de aceite: dc.date.accessioned2026-02-09T11:30:59Z-
Data de disponibilização: dc.date.available2026-02-09T11:30:59Z-
Data de envio: dc.date.issued2018-08-01-
Data de envio: dc.date.issued2018-08-01-
Data de envio: dc.date.issued2017-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br/handle/1/29864-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1141973-
Descrição: dc.descriptionLeaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI) on α-amylase, α-glycosidase, lipase, and trypsin enzymes, in the presence or not of simulated gastric fluid and to determine the content of phenolic compounds by high performance liquid chromatography. All cultivars presented the same composition in phenolic compounds, but in different proportions. The compounds identified are gallic acid, epigallocatechin gallate, syringic acid, o-coumaric acid, resveratrol, quercetin, and catechin (which was the major compound in all the cultivars evaluated). In the absence of simulated gastric fluid, it was observed different inhibitions exercised by the leaves aqueous extracts from three cultivars of P. guajava on each enzyme. In presence of simulated gastric fluid, all cultivars showed increase in the inhibition of lipase and α-glycosidase, and decrease in inhibition of α-amylase and trypsin enzymes. These results indicate that P. guajava leaves aqueous extracts from all cultivars evaluated possess potential of use as an adjuvant in the treatment of obesity and other dyslipidemias.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Publicador: dc.publisherAcademia Brasileira de Ciências-
Direitos: dc.rightsAttribution 4.0 International-
Direitos: dc.rightsAttribution 4.0 International-
Direitos: dc.rightsacesso aberto-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
Direitos: dc.rightshttp://creativecommons.org/licenses/by/4.0/-
???dc.source???: dc.sourceAnais da Academia Brasileira de Ciências-
Palavras-chave: dc.subjectMedicinal plants-
Palavras-chave: dc.subjectObesity-
Palavras-chave: dc.subjectα-amylase-
Palavras-chave: dc.subjectα-glycosidase-
Palavras-chave: dc.subjectLipase-
Palavras-chave: dc.subjectTrypsin-
Título: dc.titleAqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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