Immunological response in bovine lymph nodes stimulated with subunits vaccines

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorGomez, Gabriel Andres Tafur-
Autor(es): dc.creatorVargas, Marlene Isabel-
Autor(es): dc.creatorSalcedo, Joaquin Hernan Patarroyo-
Autor(es): dc.creatorSouza, Elisangela Neves de-
Autor(es): dc.creatorSossai, Sidimar-
Autor(es): dc.creatorArujo, Leandro de-
Autor(es): dc.creatorPeconik, Ana Paula-
Autor(es): dc.creatorKalks, Karlos Henrique Martins-
Data de aceite: dc.date.accessioned2026-02-09T11:27:10Z-
Data de disponibilização: dc.date.available2026-02-09T11:27:10Z-
Data de envio: dc.date.issued2016-12-13-
Data de envio: dc.date.issued2023-06-27-
Data de envio: dc.date.issued2016-12-13-
Data de envio: dc.date.issued2023-06-27-
Data de envio: dc.date.issued2013-
Fonte completa do material: dc.identifierhttps://repositorio.ufla.br//handle/1/57905-
Fonte completa do material: dc.identifierhttp://thescipub.com/PDF/ajisp.2013.48.57.pdf-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1141091-
Descrição: dc.descriptionThe vaccination process belongs to the public health intervention methodologies that help prevent infections. Vaccinations performed successfully in the history of medicine reported the significance of this procedure to increase the quality of life, prevent zoonoses and improve animal production. Vaccine emergence remained without exact rules for a long time, maintaining a close relationship with pathogens. However, subunit vaccines, with a difference from the classical idea of protective immunity with microorganisms showed it is possible to trigger T-dependent responses with peptide, revealing new rules for vaccine development. This vaccination process starts by the modulation chance of adaptive immune response through peptide sequences process by APCs for immune synapse formation interceded for pMHCTCR as a scaffold to T cells priming. In this way the immunological signal triggered by immune synapses is amplified in lymph nodes. As a consequence, T and B cells modulated by peptide activity interact between the B cell follicles region and T cell aggregates, which constitute the paracortical region of secondary lymphoid tissue to form connate unions as a prerequisite for clonal amplification and subsequent immunological memory. Indicating the knowledge of the mechanisms of immune response generated by peptides immunization is essential for understanding modulation, amplification and immune protection as demands for good subunits vaccine.-
Idioma: dc.languageen-
Direitos: dc.rightsrestrictAccess-
???dc.source???: dc.sourceAmerican Journal of Immunology-
Palavras-chave: dc.subjectBovine lymph nodes-
Palavras-chave: dc.subjectSynthetic peptides-
Palavras-chave: dc.subjectRecombinant peptides-
Palavras-chave: dc.subjectImmune response-
Título: dc.titleImmunological response in bovine lymph nodes stimulated with subunits vaccines-
Tipo de arquivo: dc.typeArtigo-
Aparece nas coleções:Repositório Institucional da Universidade Federal de Lavras (RIUFLA)

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