Rapid antigen test as a tool for the identification of SARS-CoV-2 infection and its potential as a self-testing device.

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Autor(es): dc.creatorFilgueiras, Priscilla Soares-
Autor(es): dc.creatorCorsini, Camila Amormino-
Autor(es): dc.creatorAlmeida, Nathalie Bonatti Franco-
Autor(es): dc.creatorPedrosa, Maria Luysa Camargos-
Autor(es): dc.creatorMiranda, Daniel Alvim Pena de-
Autor(es): dc.creatorGomes, Sarah Vieira Contin-
Autor(es): dc.creatorAssis, Jéssica Vieira de-
Autor(es): dc.creatorSilva, Raphael Antônio-
Autor(es): dc.creatorMedeiros, Maria Izabella Vieira de Assis Rocha Carvalho de-
Autor(es): dc.creatorLourenço, Adelina Junia-
Autor(es): dc.creatorBicalho, Cecilia Maria Florencio-
Autor(es): dc.creatorVilela, Raquel Virgínia Rocha-
Autor(es): dc.creatorJeremias, Wander de Jesus-
Autor(es): dc.creatorFernandes, Gabriel da Rocha-
Autor(es): dc.creatorGrenfell, Rafaella Fortini Queiroz-
Data de aceite: dc.date.accessioned2025-08-21T16:01:12Z-
Data de disponibilização: dc.date.available2025-08-21T16:01:12Z-
Data de envio: dc.date.issued2023-10-19-
Data de envio: dc.date.issued2023-10-19-
Data de envio: dc.date.issued2022-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/jspui/handle/123456789/17628-
Fonte completa do material: dc.identifierhttps://doi.org/10.1590/0037-8682-0167-2022-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1030138-
Descrição: dc.descriptionBackground: SARS-CoV-2 virus originated in Wuhan (China) in December (2019) and quickly spread worldwide. Antigen tests are rapid diagnostic tests (RDT) that produce results in 15-30 min and are an important tool for the scale-up of COVID-19 testing. COVID-19 diagnostic tests are authorized for self-testing at home in some countries, including Brazil. Widespread COVID-19 diagnostic testing is required to guide public health policies and control the speed of transmission and economic recovery. Methods: Patients with suspected COVID-19 were recruited at the Hospital da Baleia (Belo Horizonte, Brazil). The SARS-CoV-2 antigen- detecting rapid diagnostic tests were evaluated from June 2020 to June 2021 using saliva, nasal, and nasopharyngeal swab samples from 609 patients. Patient samples were simultaneously tested using a molecular assay (RT-qPCR). Sensitivity, specificity, accuracy, and positive and negative predictive values were determined using the statistical program, MedCalc, and GraphPad Prism 8.0. Results: The antigen-detecting rapid diagnostic tests displayed 98% specificity, 60% sensitivity, 96% positive predictive value, and moderate concordance with RT-qPCR. Substantial agreement was found between the two methods for patients tested < 7 days of symptom onset. Conclusions: Our findings support the use of Ag-RDT as a valuable and safe diagnostic method. Ag-RDT was also demonstrated to be an important triage tool for suspected COVID-19 patients in emergencies. Overall, Ag-RDT is an effective strategy for reducing the spread of SARS-CoV-2 and contributing to COVID-19 control.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsaberto-
Direitos: dc.rightsThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). Fonte: PDF do artigo.-
Palavras-chave: dc.subjectCovid-19-
Palavras-chave: dc.subjectRapid test-
Palavras-chave: dc.subjectSelf-test-
Título: dc.titleRapid antigen test as a tool for the identification of SARS-CoV-2 infection and its potential as a self-testing device.-
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