The overweight increases circulating inflammatory mediators commonly associated with obesity in young individuals.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorLopes, Laís Roquete-
Autor(es): dc.creatorRibeiro, Silvana Mara Luz Turbino-
Autor(es): dc.creatorFigueiredo, Vivian Paulino-
Autor(es): dc.creatorLeite, Ana Luísa Junqueira-
Autor(es): dc.creatorNicolato, Roney Luiz de Carvalho-
Autor(es): dc.creatorEstanislau, Juliana de Assis Silva Gomes-
Autor(es): dc.creatorOliveira, Fernando Luiz Pereira de-
Autor(es): dc.creatorSilva, André Talvani Pedrosa da-
Data de aceite: dc.date.accessioned2025-08-21T15:58:15Z-
Data de disponibilização: dc.date.available2025-08-21T15:58:15Z-
Data de envio: dc.date.issued2019-04-02-
Data de envio: dc.date.issued2019-04-02-
Data de envio: dc.date.issued2018-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/handle/123456789/10901-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S1043466618301777-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1028882-
Descrição: dc.descriptionObesity is a serious and growing world healthy problem affecting developed and developing countries. The new conception of obesity as a basal inflammatory condition has opened a new window of possibilities to identify inflammatory biomarkers to be used in the diagnosis or prognosis of obesity-associated comorbidities. This present work aims the identification of the adipokines (leptin and resistin), chemokines (CCL2, CCL5, CXCL16) and the BMP-2 and their association with the clinical, biochemical (fasting glucose, hemogram, cholesterol, T3, T4 and TSH) and anthropometric (weight, height, body circumferences, skinfold thickness and percentage of body fat) parameters in young adults (18–30 years old) presenting obesity and overweight. Our data showed increasing in anthropometric parameters and in the plasma inflammatory levels in those individuals presenting overweight and obesity. We observed a higher plasma levels of CCL2, CCL5, CXCL16, leptin and resistin in those overweigh and obese individuals. In addition, the CCL2, CCL5 presented a positive correlation with the body mass index and the body fat percentage. Assuming the obesity as a systemic inflammatory process, in this current study, the overweight individuals possess a close similar pattern of circulating inflammatory mediators which might be a potential risk of the development of obesity comorbidities. Further studies are still needed to precise the role of the biomarkers CCL2, CCL5, CXCL16 and BMP-2 in the clinical prognosis related to the overweight or obese individuals.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectObesity-
Palavras-chave: dc.subjectInflammatory biomarkers-
Palavras-chave: dc.subjectAdipokines-
Palavras-chave: dc.subjectChemokines-
Título: dc.titleThe overweight increases circulating inflammatory mediators commonly associated with obesity in young individuals.-
Aparece nas coleções:Repositório Institucional - UFOP

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