The timeline of neuronal and glial alterations in experimental obesity.

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorEngel, Daiane Fátima-
Autor(es): dc.creatorVelloso, Licio Augusto-
Data de aceite: dc.date.accessioned2025-08-21T15:55:34Z-
Data de disponibilização: dc.date.available2025-08-21T15:55:34Z-
Data de envio: dc.date.issued2023-01-15-
Data de envio: dc.date.issued2023-01-15-
Data de envio: dc.date.issued2021-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/jspui/handle/123456789/15942-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0028390822000429?via%3Dihub-
Fonte completa do material: dc.identifierhttps://doi.org/10.1016/j.neuropharm.2022.108983-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1027628-
Descrição: dc.descriptionIn experimental models, hypothalamic dysfunction is a key component of the pathophysiology of diet-induced obesity. Early after the introduction of a high-fat diet, neurons, microglia, astrocytes and tanycytes of the mediobasal hypothalamus undergo structural and functional changes that impact caloric intake, energy expen- diture and systemic glucose tolerance. Inflammation has emerged as a central component of this response, and as in other inflammatory conditions, there is a time course of events that determine the fate of distinct cells involved in the central regulation of whole-body energy homeostasis. Here, we review the work that identified key mechanisms, cellular players and temporal features of diet-induced hypothalamic abnormalities.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectProopiomelanocortin-
Palavras-chave: dc.subjectAstrocyte-
Palavras-chave: dc.subjectMicroglia-
Palavras-chave: dc.subjectTanycyte-
Título: dc.titleThe timeline of neuronal and glial alterations in experimental obesity.-
Aparece nas coleções:Repositório Institucional - UFOP

Não existem arquivos associados a este item.