Targeting Leishmania promastigotes and amastigotes forms through amino acids and peptides : a promising therapeutic strategy.

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorRegistre, Charmante-
Autor(es): dc.creatorSilva, Luciana Miranda-
Autor(es): dc.creatorRegistre, Farah-
Autor(es): dc.creatorSoares, Rodrigo Dian de Oliveira Aguiar-
Autor(es): dc.creatorRúbio, Karina Taciana Santos-
Autor(es): dc.creatorCarneiro, Simone Pinto-
Autor(es): dc.creatorSantos, Orlando David Henrique dos-
Data de aceite: dc.date.accessioned2025-08-21T15:53:45Z-
Data de disponibilização: dc.date.available2025-08-21T15:53:45Z-
Data de envio: dc.date.issued2025-01-29-
Data de envio: dc.date.issued2025-01-29-
Data de envio: dc.date.issued2023-
Fonte completa do material: dc.identifierhttps://www.repositorio.ufop.br/handle/123456789/19646-
Fonte completa do material: dc.identifierhttps://pubs.acs.org/doi/10.1021/acsinfecdis.4c00089-
Fonte completa do material: dc.identifierhttps://doi.org/10.1021/acsinfecdis.4c00089?urlappend=%3Fref%3DPDF&jav=VoR&rel=cite-as-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1026814-
Descrição: dc.descriptionMillions of people worldwide are affected by leishmaniasis, caused by the Leishmania parasite. Effective treatment is challenging due to the biological complexity of the parasite, drug toxicity, and increasing resistance to conventional drugs. To combat this disease, the development of specific strategies to target and selectively eliminate the parasite is crucial. This Review highlights the importance of amino acids in the developmental stages of Leishmania as a factor determining whether the infection progresses or is suppressed. It also explores the use of peptides as alternatives in parasite control and the development of novel targeted treatments. While these strategies show promise for more effective and targeted treatment, further studies to address the remaining challenges are imperative.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectLeishmania-
Palavras-chave: dc.subjectPromastigotes-
Palavras-chave: dc.subjectAmastigotes-
Palavras-chave: dc.subjectLeishmaniasis-
Palavras-chave: dc.subjectNovel treatments-
Título: dc.titleTargeting Leishmania promastigotes and amastigotes forms through amino acids and peptides : a promising therapeutic strategy.-
Aparece nas coleções:Repositório Institucional - UFOP

Não existem arquivos associados a este item.