Tapentadol, an opioid as a strategy for the treatment of chronic pain? : a narrative review.

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorMarrafon, Danielle Aparecida Ferreira de Oliveira-
Autor(es): dc.creatorSilva, Alessandra Oliveira-
Autor(es): dc.creatorAmorim, Ana Flavia da Silva-
Autor(es): dc.creatorBarros, Carlos Marcelo de-
Autor(es): dc.creatorRascado, Ricardo Radighieri-
Autor(es): dc.creatorCeron, Carla Speroni-
Autor(es): dc.creatorReis, Tiago Marques dos-
Autor(es): dc.creatorPodestá, Márcia Helena Miranda Cardoso-
Autor(es): dc.creatorAlmeida, Daniel Augusto de Faria-
Autor(es): dc.creatorPacheco, Larissa Helena Lobo Torres-
Autor(es): dc.creatorPereira, Marília Gabriella Alves Goulart-
Data de aceite: dc.date.accessioned2025-08-21T15:49:58Z-
Data de disponibilização: dc.date.available2025-08-21T15:49:58Z-
Data de envio: dc.date.issued2025-02-27-
Data de envio: dc.date.issued2022-
Fonte completa do material: dc.identifierhttps://www.repositorio.ufop.br/handle/123456789/19816-
Fonte completa do material: dc.identifierhttps://doi.org/10.18231/j.jpbs.2023.004-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1025260-
Descrição: dc.descriptionChronic pain affects approximately 30 % of the world population. Tapentadol can be an analgesic option for patients who do not respond adequately to commonly used opioids. This study reviewed the general aspects of Tapentadol pain treatment and its possible association with increased oxidative stress, as well as the benefits of its association with antioxidant substances. The search was carried out in the Medline (Pubmed), Scopus,Web of Science, and Google academic databases, including studies since the registration of the drug in 2008. The selected articles were those related to the use of Tapentadol for chronic moderate to severe pain, but not cancer-related pain, in adults and the elderly. Tapentadol is a μ opioid receptors agonist and inhibits noradrenaline reuptake. Although Tapentadol causes fewer adverse effects than other conventional opioids, studies have shown the induction of oxidative stress by this drug, but without having elucidated the mechanisms.-
Formato: dc.formatapplication/octet-stream-
Idioma: dc.languageen-
Direitos: dc.rightsaberto-
Direitos: dc.rightsThis is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. Fonte: PDF do artigo.-
Palavras-chave: dc.subjectAdverse effects-
Palavras-chave: dc.subjectChronic pain-
Palavras-chave: dc.subjectOxidative stress-
Título: dc.titleTapentadol, an opioid as a strategy for the treatment of chronic pain? : a narrative review.-
Aparece nas coleções:Repositório Institucional - UFOP

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