The effects of different ventilatory modes in female adult rats submitted to mechanical ventilation.

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Autor(es): dc.creatorAlmeida, Matheus Rocha-
Autor(es): dc.creatorHorta, Jacques Gabriel Álvares-
Autor(es): dc.creatorMatos, Natália Alves de-
Autor(es): dc.creatorSouza, Ana Beatriz Farias de-
Autor(es): dc.creatorCastro, Thalles de Freitas-
Autor(es): dc.creatorCândido, Leandro da Silva-
Autor(es): dc.creatorAndrade, Mônica Campos-
Autor(es): dc.creatorCangussú, Silvia Dantas-
Autor(es): dc.creatorCosta, Guilherme de Paula-
Autor(es): dc.creatorSilva, André Talvani Pedrosa da-
Autor(es): dc.creatorBezerra, Frank Silva-
Data de aceite: dc.date.accessioned2025-08-21T15:36:00Z-
Data de disponibilização: dc.date.available2025-08-21T15:36:00Z-
Data de envio: dc.date.issued2021-09-23-
Data de envio: dc.date.issued2021-09-23-
Data de envio: dc.date.issued2020-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/jspui/handle/123456789/13796-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/abs/pii/S1569904820302421?via%3Dihub-
Fonte completa do material: dc.identifierhttps://doi.org/10.1016/j.resp.2020.103583-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1019396-
Descrição: dc.descriptionThis study aimed to analyze the effects of volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) modes in female Wistar rats. 18 Wistar female adult rats were divided into three groups: control (CG), pressure-controlled ventilation (PCVG), and volume-controlled ventilation (VCVG). PCVG and VCVG were submitted to MV for one hour with a tidal volume (TV) of 8 mL/Kg, respiratory rate of 80 breaths/min, and positive end-expiratory pressure of 0 cmH2O. At the end of the experiment, all animals were euthanized. The neutrophils and lymphocytes influx to lung were higher in VCVG and PCVG compared to CG. The activities of superoxide dismutase, catalase and myeloperoxidase were higher in PCVG compared to CG. There was an increase in lipid peroxidation and protein oxidation in PCVG compared to CG. The levels of CCL3 and CCL5 were higher in PCVG compared to CG. In conclusions, the PCV mode promoted structural changes in the lung parenchyma, redox imbalance and inflammation in healthy adult female rats submitted to MV.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectLung-
Título: dc.titleThe effects of different ventilatory modes in female adult rats submitted to mechanical ventilation.-
Aparece nas coleções:Repositório Institucional - UFOP

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