Poly(methylmethacrylate-co-dimethyl acrylamide)–silver nanocomposite prevents biofilm formation in medical devices.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorPerasoli, Fernanda Barçante-
Autor(es): dc.creatorSilva, Luan Silvestro Bianchini-
Autor(es): dc.creatorFigueiredo, Bruna Inez Carvalho de-
Autor(es): dc.creatorPinto, Isabelle Cristina-
Autor(es): dc.creatorAmaro, Lorrane Jenifer Ferreira-
Autor(es): dc.creatorBastos, Juliana Cristina dos Santos Almeida-
Autor(es): dc.creatorCarneiro, Simone Pinto-
Autor(es): dc.creatorAraújo, Vânia P. R.-
Autor(es): dc.creatorBeato, Felipe Rafael Gomes-
Autor(es): dc.creatorBarboza, Ana Paula Moreira-
Autor(es): dc.creatorTeixeira, Luiz Fernando de Medeiros-
Autor(es): dc.creatorGallagher, Maurice Patrick-
Autor(es): dc.creatorBradley, Mark-
Autor(es): dc.creatorVenkateswaran, Seshasailam-
Autor(es): dc.creatorSantos, Orlando David Henrique dos-
Data de aceite: dc.date.accessioned2025-08-21T15:29:20Z-
Data de disponibilização: dc.date.available2025-08-21T15:29:20Z-
Data de envio: dc.date.issued2025-01-07-
Data de envio: dc.date.issued2025-01-07-
Data de envio: dc.date.issued2023-
Fonte completa do material: dc.identifierhttps://www.repositorio.ufop.br/handle/123456789/19405-
Fonte completa do material: dc.identifierhttps://www.tandfonline.com/doi/full/10.1080/17435889.2024.2345044-
Fonte completa do material: dc.identifierhttps://doi.org/10.1080/17435889.2024.2345044-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1016474-
Descrição: dc.descriptionAim: To investigate whether medical devices coated with a synthesized nanocomposite of poly(methylmethacrylate-co-dimethyl acrylamide) (PMMDMA) and silver nanoparticles (AgNPs) could improve their antibiofilm and antimicrobial activities. We also investigated the nanocomposite’s safety. Materials & methods: The nanocomposite was synthesized and characterized using analytical techniques. Medical devices coated with the nanocomposite were evaluated for bacterial adhesion and hemolytic activity in vitro. Results: The nanocomposite formation was demonstrated with the incorporation of AgNPs into the polymer matrix. The nanocomposite proved to be nonhemolytic and significantly inhibited bacterial biofilm formation. Conclusion: The PMMDMA-AgNPs nanocomposite was more effective in preventing biofilm formation than PMMDMA alone and is a promising strategy for coating medical devices and reducing mortality due to hospital-acquired infections.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectAntiadherent effects-
Palavras-chave: dc.subjectAntimicrobial effects-
Palavras-chave: dc.subjectNonhemolytic-
Palavras-chave: dc.subjectPoly(methylmethacrylate-co-dimethylacrylamide)-
Palavras-chave: dc.subjectSilver nanoparticles-
Título: dc.titlePoly(methylmethacrylate-co-dimethyl acrylamide)–silver nanocomposite prevents biofilm formation in medical devices.-
Aparece nas coleções:Repositório Institucional - UFOP

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