Progressive strength training can reverse sarcopenia stage in middle-aged and older adults regardless of their genetic profile.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorSilva, Ana Carolina da-
Autor(es): dc.creatorSilva, Vinícius Camael Mapa-
Autor(es): dc.creatorFerreira Júnior, João Batista-
Autor(es): dc.creatorOliveira, Emerson Cruz de-
Autor(es): dc.creatorBecker, Lenice Kappes-
Autor(es): dc.creatorRosse, Izinara Cruz-
Autor(es): dc.creatorCoelho, Daniel Barbosa-
Data de aceite: dc.date.accessioned2025-08-21T15:29:02Z-
Data de disponibilização: dc.date.available2025-08-21T15:29:02Z-
Data de envio: dc.date.issued2025-03-07-
Data de envio: dc.date.issued2023-
Fonte completa do material: dc.identifierhttps://www.repositorio.ufop.br/handle/123456789/19872-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0167494323002601-
Fonte completa do material: dc.identifierhttps://doi.org/10.1016/j.archger.2023.105182-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1016334-
Descrição: dc.descriptionThe aim of this study was to verify the association of the ACTN3-R577X polymorphism with sarcopenia stage, according to the Revised European Consensus on the Definition and Diagnosis of Sarcopenia, in middle-aged and older adults, pre- and post- ST. In the 12-week longitudinal study, 71 middle-aged and older adults were evaluated; the participants were assigned to either control or intervention group. The intervention group underwent progressive ST three times a week. All participants underwent blood collection, DNA extraction, genotyping of the ACTN3-R577X polymorphism, anthropometric evaluations, and diagnostic tests for sarcopenia. The last two tests were repeated after 12 weeks. No association of the ACTN3-R577X polymorphism with sarcopenia stage was observed before and after 12 weeks. However, the intervention group remained non-sarcopenic (n = 25, p <0.05) or achieved changes in sarcopenia stage (from sarcopenic to non-sarcopenic) (n = 13, p <0.05). Our study demonstrates that progressive ST performed regularly can reverse or prevent sarcopenia regardless of genotype for the ACTN3-R577X polymorphism.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectα-actinin 3-
Palavras-chave: dc.subjectStrength-
Palavras-chave: dc.subjectMuscle mass-
Palavras-chave: dc.subjectFunctional capacity-
Título: dc.titleProgressive strength training can reverse sarcopenia stage in middle-aged and older adults regardless of their genetic profile.-
Aparece nas coleções:Repositório Institucional - UFOP

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