Clustered cardiovascular risk factors are associated with inflammatory markers in adolescents.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorSilva, Carla Teixeira-
Autor(es): dc.creatorCândido, Ana Paula Carlos-
Autor(es): dc.creatorPala, Daniela-
Autor(es): dc.creatorBarbosa, Priscila Oliveira-
Autor(es): dc.creatorCoelho, George Luiz Lins Machado-
Autor(es): dc.creatorOliveira, Fernando Luiz Pereira de-
Autor(es): dc.creatorVolp, Ana Carolina Pinheiro-
Autor(es): dc.creatorFreitas, Renata Nascimento de-
Data de aceite: dc.date.accessioned2025-08-21T15:28:50Z-
Data de disponibilização: dc.date.available2025-08-21T15:28:50Z-
Data de envio: dc.date.issued2017-09-26-
Data de envio: dc.date.issued2017-09-26-
Data de envio: dc.date.issued2017-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/handle/123456789/8799-
Fonte completa do material: dc.identifierhttps://www.karger.com/Article/FullText/458767-
Fonte completa do material: dc.identifierhttps://doi.org/10.1159/000458767-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1016236-
Descrição: dc.descriptionBackground: Clusters of cardiovascular risk (CVR) factors are associated with an increased risk of developing cardiovascular diseases (CVDs). This cross-sectional study assessed the associations between classic CVR factor clusters and inflammatory markers in Brazilian adolescents. Methods: Measurements included anthropometric, clinical and biochemical parameters and selected inflammatory markers in 487 adolescents (236 boys/251 girls; 12.06 ± 1.41 years). Results: After stratifying the population by gender and adjusting for potential confounding variables, principal component analysis was performed and it produced 5 independent components in both genders: adiposity, glucose metabolism, blood pressure, high-density lipoprotein (HDL)/triacylglycerols (TG), and cholesterol/low-density lipoprotein. Glucose metabolism was inversely associated with interleukin-1β (IL-1β) in both genders ( r = –0.026; r = –0.021); blood pressure was inversely associated with tumor necrosis factor alpha (TNF-α) in girls ( r = –0.046); HDL/TG was positively associated with interleukin-6 in girls ( r = 0.012), with IL-1β ( r = 0.010) TNF-α ( r = 0.045) in boys, and inversely associated with adiponectin in both genders ( r = –0.015; r = –0.013). Conclusion: The results suggest that lipid metabolism alterations, as potential early events in the development of CVDs, have a strong link to the inflammatory process, in contrast to other clusters of risk factors.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectCytokines-
Palavras-chave: dc.subjectCardiovascular disease - risk factors-
Palavras-chave: dc.subjectPrincipal components analysis-
Título: dc.titleClustered cardiovascular risk factors are associated with inflammatory markers in adolescents.-
Aparece nas coleções:Repositório Institucional - UFOP

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