Hypovitaminosis D is associated with visceral adiposity, high levels of low-density lipoprotein and triglycerides in alternating shift workers.

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Autor(es): dc.creatorBatista, Aline Priscila-
Autor(es): dc.creatorAmbrosim, Ticiana Vazzoler-
Autor(es): dc.creatorNascimento Neto, Raimundo Marques do-
Autor(es): dc.creatorPimenta, Fausto Aloísio Pedrosa-
Autor(es): dc.creatorFreitas, Silvia Nascimento de-
Autor(es): dc.creatorLauria, Márcio Weissheimer-
Autor(es): dc.creatorCoelho, George Luiz Lins Machado-
Data de aceite: dc.date.accessioned2025-08-21T15:22:59Z-
Data de disponibilização: dc.date.available2025-08-21T15:22:59Z-
Data de envio: dc.date.issued2017-09-22-
Data de envio: dc.date.issued2017-09-22-
Data de envio: dc.date.issued2016-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/handle/123456789/8774-
Fonte completa do material: dc.identifierhttps://doi.org/http://dx.doi.org/10.14740/jem340w-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1012663-
Descrição: dc.descriptionBackground: Studies suggest that there is a strong association between low vitamin D levels and cardiovascular disease (CVD) and its risk factors (RFs). Hypovitaminosis D (25(OH)D < 30 ng/mL or 75 nmol/L) is a recent public health problem that has reached different populations. The objective of the study was to investigate whether hypovitaminosis D is an additional mechanism to explain the disturbances in the lipid profile as well as the excess of abdominal fat presented by alternating shift workers of a mining company in the region of Inconfidentes, Minas Gerais, Brazil. Methods: A cross-sectional study was conducted in a sample of 391 adult males, aged 20 - 57 years old and working alternating shifts, who had at least one risk criterion for CVD. Demographic, behavioral, clinical, and anthropometric and body composition variables were obtained. A blood sample was drawn for determining 25(OH) D, parathyroid hormone intact molecule, lipid profile, blood glucose, insulin, C-reactive protein, and adipokines. Results: The average age of the 391 study participants was 36.1 ± 7.3 years. The percentage of hypovitaminosis D and dyslipidemia was 73% and 74.2%, respectively. Excess visceral fat was significant in the hypovitaminosis D group, with an odds ratio (OR) of 2.4 (95% confidence interval (CI): 1.1 - 5.2). Dyslipidemia showed 25(OH)D levels significantly lower (OR: 2.7, 95% CI: 1.6 - 4.3) than in individuals with normal levels of cholesterol and fractions, and triglycerides. After adjusted the analysis by age and seasonality, the vitamin levels had a significant inverse association and dose-dependent with lowdensity lipoprotein (OR: 5.9), triglycerides (OR: 2.3) and visceral fat area (OR: 2.4). Conclusion: Hypovitaminosis D and dyslipidemia were found in the majority of our mining company shift workers. Furthermore, excess visceral adiposity, hypertriglyceridemia and high low-density lipoprotein cholesterol levels are strong predictors of hypovitaminosis D.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsaberto-
Direitos: dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: o próprio artigo.-
Palavras-chave: dc.subjectAlternating shift workers-
Palavras-chave: dc.subjectOccupational health-
Palavras-chave: dc.subjectLowdensity lipoprotein-
Palavras-chave: dc.subjectTriglycerides-
Palavras-chave: dc.subjectAtherosclerosis-
Título: dc.titleHypovitaminosis D is associated with visceral adiposity, high levels of low-density lipoprotein and triglycerides in alternating shift workers.-
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